1.
Rev. bras. pesqui. méd. biol
; Braz. j. med. biol. res;23(12): 1233-5, 1990. ilus
Article
de Anglais
| LILACS
| ID: lil-103649
RÉSUMÉ
Rabbit and, to a lesser extent, human immunoglobulins (IgGs) are cleaved by snake venoms. The snake venom proteases active on IgGs release fragments which behave on SDS-PAGE like Fab units similar to those release by the thiol-activated enzymes. However, in contrast to the cysteine proteases, the activity of snake venom proteases on IgGs is not only blocked by metal chelating agents but is also inhibited by thiol compounds. The snake enzymes active on IgG are metalloproteases
Sujet(s)
Lapins , Rats , Animaux , Humains , Fragments Fab d'immunoglobuline/métabolisme , Immunoglobuline G/métabolisme , Venins de serpent/métabolisme , Électrophorèse sur gel de polyacrylamide , Peptide hydrolases/métabolisme , Venins de serpent/enzymologie
2.
Rev. bras. pesqui. méd. biol
; Braz. j. med. biol. res;18(3): 337-40, 1985. ilus
Article
de Anglais
| LILACS
| ID: lil-27418