The association between Betel Quid Chewing and Metabolic Syndrome among urban adults in Mandalay District of Myanmar / Journal of the ASEAN Federation of Endocrine Societies

Background@#As the prevalence of metabolic syndrome, obesity and diabetes increase worldwide, the need to identify modifiable lifestyle risk factors also increases, especially those that may be relatively unique to a specific population. To explore a possible association between betel quid chewing and metabolic syndrome, a community-based cross-sectional study was conducted.@*Methodology@#Three hundred ninety-one (391) adults were interviewed and the following parameters were measured: triglycerides, HDL-cholesterol, glucose, waist circumference, body mass index and blood pressure. Multiple logistic regression was used to determine the association between betel quid chewing and metabolic syndrome while controlling for confounders.@*Results@#The prevalence of metabolic syndrome was similar in chewers and non-chewers, 50% and 49%, respectively. After controlling for other factors, development of metabolic syndrome was positively associated with number of betel quid chewed per day, age greater than 40 years , and a positive family history of hypertension and diabetes. Regarding the duration of betel chewing, when analyzed by sex, the risk was doubled in men compared to non-chewers (OR 2.15; 95% CI = 1.21, 3.84]). As a result, a man chewing more than 10 pieces (OR 2.49; 95% CI = 1.36, 4.57]) of betel quids per day for more than 10 years had a two-fold increased chance of developing the metabolic syndrome.@*Conclusions@#Frequency and duration of betel quid chewing may represent a behavioral lifestyle target for approaches to reduce the incidence of metabolic syndrome.

AFES A.S.-O.N.E.: ASEAN survey of needs in Endocrinologyin the time of the COVID-19 pandemic / Journal of the ASEAN Federation of Endocrine Societies

Objectives@#The COVID-19 pandemic has made a major impact on hospital services globally, including the care of persons with diabetes and endocrine disorders. The aim of this study is to describe the epidemiology of COVID-19 in the ASEAN Federation of Endocrine Societies (AFES) member countries; to describe challenges, changes and opportunities in caring for patients with endocrine diseases, as well as in fellowship training programs, and endocrine-related research in the AFES countries.@*Methodology@#The AFES ASEAN Survey Of Needs in Endocrinology (AFES A.S.-O.N.E.) was an open-ended questionnaire that was sent to the presidents and representatives of the AFES member countries by email. Responses from Societies were collated and synthesized to obtain perspectives on the emergent issues in endocrinology in the Southeast Asian region during this pandemic.@*Results@#The burden of COVID-19 cases varied widely across the AFES member countries, with the least number of cases in Vietnam and Myanmar, and the greatest number of cases in either the most populous countries (Indonesia and the Philippines), or a country with the highest capability for testing (Singapore). The case fatality rate was also the highest for Indonesia and the Philippines at around 6%, and lowest for Vietnam at no fatalities. The percentage with diabetes among patients with COVID-19 ranged from 5% in Indonesia to 20% in Singapore, approximating the reported percentages in China and the United States. The major challenges in managing patients with endocrine diseases involved inaccessibility of health care providers, clinics and hospitals due to the implementation of lockdowns, community quarantines or movement control among the member countries. This led to disruptions in the continuity of care, testing and monitoring, and for some, provision of both preventive care and active management including surgery for thyroid cancer or pituitary and adrenal tumors, and radioactive iodine therapy. Major disruptions in the endocrine fellowship training programs were also noted across the region, so that some countries have had to freeze hiring of new trainees or to revise both program requirements and approaches to training due to the closure of outpatient endocrine clinics. The same observations are seen for endocrine-related researches, as most research papers have focused on the pandemic. Finally, the report ends by describing innovative approaches to fill in the gap in training and in improving patient access to endocrine services by Telemedicine.@*Conclusion@#The burden of COVID-19 cases and its case fatality rate varies across the AFES member countries but its impact is almost uniform: it has disrupted the provision of care for patients with endocrine diseases, and has also disrupted endocrine fellowship training and endocrine-related research across the region. Telemedicine and innovations in training have been operationalized across the AFES countries in an attempt to cope with the disruptions from COVID-19, but its over-all impact on the practice of endocrinology across the region will only become apparent once we conquer this pandemic.

The use of epidural analgesia in elective lower segment caesarean section at North Okkalapa General Hospital

A prospective study on the use of epidural anaesthesia in lower segment caesarean section at NOGH was carried out on 41 patients who had been admitted to NOGH from the 1st May 1995 to the 30th April 1996. All the necessary preoperative assessments were done. Epidural analgesia, but using a combination of 0.5 per cent Marcaine and 2 per cent lignocaine was given. the mean duration of induction delivery period was 15 minutes, mean one-minute Apgar score was 7.95. About seventy three per cent (73.17 per cent) of the patients could start breast feeding soon after delivery in the operation theatre and the remaining patients could breast feed their babies soon after leaving the theatre. No serious complication was encountered apart from 7.3 per cent of the patients who had minor complications. The mean duration of postoperative analgesia was 10.46 hours and the mean pain score 1.6. Among these, 39.02 per cent did not require any post-operative analgesia, 39.02 per cent were relieved by placebo injection, 12.19 per cent by injection Diazepam, 7.33 per cent by injection volteran while 2.44 per cent required injection morphine.

The use of epidural analgesia in elective lower segment caesarean section at North Okkalapa General Hospital

A prospective study on the use of epidural anaesthesia in lower segment caesarean section at NOGH was carried out on 41 patients who had been admitted to NOGH from the 1st May 1995 to the 30th

Serum calcium in normal and preeclamptic pregnant Myanmar women

To study the changes during normal pregnancy and in preeclampsia, serum calcium concentration was measured in 26 apparently healthy pregnant Myanmar women and in 15 preeclamptic patients. They were 20-40 years of age. In healthy pregnant women, serum total calcium levels measured at 24th week, 28th week, 32nd week and 36th week of gestation were 2.45 + or - 0.30 mmol/1, 2.47 + or - 0.29 mmol/1, 2.41 + or - 0.29 mmol/1 and 2.46 + or - 0.29 mmol/1 respectively and ionized calcium levels at these periods were 1.24 + or - 0.15 mmol/1, 1.23 + or - 0.14 mmol/1, and 1.20 + or - 0.16 mmol/1 respectively. In preeclamptic patients, the mean serum total calcium level (2.26 + or - 0.24 mmol/1) was significantly lower than that (2.52 + or - 0.23 mmol/1) of 0.27 mmol/1) and ionized calcium level (1.23 + or - 0.14 mmol/1) of preeclamptic patients were not significantly different from those (2.43 + or - 0.24 mmol/1 and 1.24 + or - 0.13 mmol/1 respectively) of control.