use of chicken ileum as an alternative isolated preparation for experimental pharmacology

Objective: to evaluate the use of chicken ileum preparation for graded dose response relationship of acetylcholine

Material and Methods: the isolated chicken ileum was obtained from market and processed for pharmacological testing in Tyrode's solution. Graded dose response of acetylcholine on this preparation was studied and recorded

Results: the responses obtained by this tissue preparation were similar to those with rabbit ileum preparation which is usually used in pharmacology experimentations in our set-up

Conclusion: the chicken ileum can be used successfully in routine pharmacology experiments in place of rabbit ileum preparation as it is cheaper and easily available