Résumé
Background: Hydatid cyst is caused by Echinococcus granulosus and human is the accidental host. The most common sites of involvement are the liver and lungs, and involvement of other organs is less common. Ocular involvement of hydatid cyst is one of the most uncommon manifestations of hydatid cyst
Cases Report: The case was a 40-year-old woman with a retrobulbar cystic lesion who was examined for the left eye pain and then proptosis. With the initial diagnosis of retrobulbar tumor, the patient underwent surgery and the removed mass was sent to the pathology laboratory. Since the result indicated the existence of a hydatid cyst, the patient was referred to the infectious service and was treated with albendazole
Conclusion: Although the ocular involvement of hydatid cyst is uncommon, it should be considered as a differential diagnosis in patients with proptosis in the endemic areas
Résumé
Background: Hepatitis C infection is a worldwide problem. In Iran, hepatitis C virus [HCV] infection prevalence is about 1-2%. A combination therapy of pegylated interferon alfa-2a and ribavirin [PEG-IFNalpha/RBV] is a standard treatment, but our aim was to determine the efficacy and safety of dual PEG-IFNalpha/RBV therapy in treating patients infected with HCV in Iranian context
Materials and Methods: This study is a cross sectional conducted among 98 HCV infected patients who were admitted to Labbafinezhad Hospital [Tehran, Iran] for treatment from April 2014 to September 2016. Patients were medicated with Peg Interferon Alfa [INFalpha] and Ribavirin [RBV]. Lab tests were monitored through the study and dose modification was done. We also assessed treatment responses at the defined time points. The incidences of adverse events were determined either. We investigated independent predictors of sustained virologic response [SVR] in the participants. Finally, data were gathered and statistical analysis was completed
Results: Eighty-eight percent of patients were male and 11.2% were female. Mean age was 43.44 years. Patients were mostly male, single, with nongovernmental business and low level of education. Risk factors were known to be addiction with non-injectable substances and phlebotomy. Myalgia, fatigue and malaises were the most common complications and suicide intention was the least one. SVR was estimated 76.7%. AST and ALT were significantly reduced in treatment period
Conclusion: Peg INFa and RBV are effective in treating HCV infection