Elevated concentration of s-ICAM-1 and s-VCAM-1 in IDDM patients with hearingloss

This study was carried out on IDDM patients classified into group I and group II according to the absence or presence of impairment of hearing, respectively. Impairment of hearing was determined by using pure tone audiometry [PTA], distortion product otoacoustic emissions [DPOAE] and brain stem evoked response audiometer [ABR]. The selection of cases, the idea of the study, interpretation of data and comments were presented. It was concluded that soluble VCAM- 1 and s- ICAM-1 were positively associated with the risk for hearing loss in IDDM patients. Soluble VCAM-1 and sICAM-1 may be useful indicators of hearing loss in IDDM patients