Piper nigrum Derived Phytochemicals against Gonorrhoea

Phytochemicals from Piper nigrum plant extract are traditionally used to cure Gonorrhoea. It is caused by Neisseria gonnorrhoeae. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that p-cymenecan effectively deactivate the dihydrofolate reductase enzyme thereby interrupting the life cycle of the organism