RÉSUMÉ
Background: Wrinkles on the face and aging of the skin are an undesirable effect of photodamage and ultraviolet radiation. Serum has a quick absorption and ability to penetrate deep layers of the skin, as well as a non-oily finish and a deep formula with a very high amount of active ingredients. Methods: In this study, we have formulated and evaluated a face serum containing combination of aqueous extract of fenugreek seed and lemon oil. Results: Facial serum was tested for its pH, physical appearance, viscosity, microbial testing, cyclic temperature test, etc. The results of the stability study show that there was no change in visual acuity, homogeneity. Conclusions: Serum containing Fenugreek extract have been able to cure bacterial infections and inflammations of facial skin, and other signs also moistens the skin without any side effects making skin soft, smooth and supple.
RÉSUMÉ
Treatment of rats with paracetamol and CCl4 produced a significant increase in the levels of serum glutamate pyruvate transaminase (SGPT), serum glutamate oxaloacetate transaminase (SGOT), alkaline phosphatase (ALP), total and direct bilirubin. Rats pretreated with methanolic extract of roots of H. indicus (100-500 mg/kg body weight, po) exhibited rise in the levels of these enzymes but it was significantly less as compared to those treated with paracetamol or CCl4 alone. The results of methanolic extract of H. indicus were comparable with the standard hepatoprotective agent silymarin (100 mg/kg). Maximum hepatoprotective effect was found to be at the dose of 250 mg/kg body weight in case of CCl4 induced hepatic damage while 500 mg/kg body weight in case of paracetamol induced hepatic damage. The results suggest that methanolic extract of H. indicus roots possesses a potential antihepatotoxic activity.