Colonic Transposition for Corrosive Esophageal Strictures - Our Experience

Introduction: Alkaline caustics and acids are the most common chemicals implicated in caustic burns. Stricture formation with inability to swallow food after the injury is inevitable in some cases. As for the complications and ineffectiveness of the dilation in more severe strictures, colonic transposition serves as a better replacement for the esophagus. Aim: This study aims to study the adequacy of colonic transposition done for cases of corrosive esophageal strictures and to discuss the complications and their management and the outcome of therapeutic measures employed. Materials and Methods: A total of eight adults with corrosive esophageal strictures were studied at M S Ramaiah Teaching Hospital for 2 years from October 2012 to December 2014. Results: Of the eight patients, who were studied, five were male and three were female. Intentional mode of corrosive intake was higher (n = 5) and acidic corrosive was more commonly ingested (n = 6). Upper esophageal stricture was seen in five patients. Colonic transposition + feeding jejunostomy (FJ) was done in eight patients, of which two patients underwent transhiatal esophagectomy+colonic transposition+FJ. Complications were seen in 50% of the patients with 38% having anastomotic leak and 12% having anastomotic stricture which were managed conservatively. All the eight patients had improved outcome of life. Conclusion: Colonic transposition is a good and effective conduit for the management of corrosive esophageal strictures.

Inhibition of Aspergillus flavus colonization and aflatoxin (AfB1) in peanut by methyleugenol.

Methyleugenol is naturally occurring substance in oils and fruits and in various foods as flavoring agent. Effect of this methyleugenol in inhibiting A. flavus colonization and aflatoxin production on peanut pods and kernels has been studied. Spray of methyleugenol (0.5%) on peanut pods and kernels checked the colonization of A. flavus and aflatoxin synthesis. This chemical can be used as both prophylactic or post infection spray on peanut pods before storage. It is the first report on the inhibition of A. flavus by methyleugenol on peanut.