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1.
J Indian Med Assoc ; 2005 Jul; 103(7): 376, 378-80, 382
Article Dans Anglais | IMSEAR | ID: sea-104127

Résumé

Diabetes is a worldwide medical problem and is a significant cause of morbidity and mortality. It has considerable impact on both the patient and the society because it typically affects individuals in their most productive years. It is also one of the leading causes of blindness and visual impairment. A person with diabetes has 25 times the risk of blindness compared to a non-diabetic. This article reviews the variety of ways in which the eye and its adnexa can be involved in diabetes mellitus.


Sujets)
Complications du diabète/anatomopathologie , Rétinopathie diabétique/anatomopathologie , Maladies de l'oeil/anatomopathologie , Humains
2.
J Indian Med Assoc ; 2004 Dec; 102(12): 708, 710, 712 passim
Article Dans Anglais | IMSEAR | ID: sea-105885

Résumé

Glaucoma is the second largest blinding disorder, after cataract, affecting about 67 million people worldwide. In India about 1.5 million people are blind due to glaucoma. Primary open angle glaucoma is the major sub-type of glaucoma affecting all ages and is genetically complex. Myocilin and optineurin are two different genes that have been implicated for primary open angle glaucoma. This review is focused on the studies being conducted in India on primary open angle glaucoma to identify the molecular defects and new directions undertaken using bioinformatic approaches towards a better understanding of the disease.


Sujets)
Cécité/étiologie , Chromosomes humains de la paire 10/génétique , Biologie informatique , Protéines du cytosquelette/génétique , Protéines de l'oeil/génétique , Glaucome à angle ouvert/classification , Glycoprotéines/génétique , Humains , Inde , Facteur de transcription TFIIIA/génétique , Troubles de la vision/étiologie
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