Late mesenteric ischemia after Sars-Cov-2 infection: case report / Isquemia mesentérica tardia após infecção por Sars-Cov-2: relato de caso

Abstract The purpose of this article is to report the case of a 53-year-old black man, with no previous comorbidities, who presented 48 days after a confirmed diagnosis of COVID-19, complaining of an initially insidious epigastric pain that had progressed to severe pain radiating to the interscapular vertebral region, with hyporexia and episodes of projectile vomiting, with no nausea or fever. Laboratory tests revealed no signs of acute infection or pancreatic injury. Abdominal computed tomography showed dilated, fluid-filled small bowel loops with thickened walls. After clinical treatment, the patient developed persistent abdominal pain. An exploratory laparotomy was performed, finding two sites of small bowel stenosis, with no extrinsic cause, and signs of local ischemia and considerable distension of jejunal and ileal loops. After enterectomy and side-to-side enteroanastomosis, the patient recovered satisfactorily and was discharged with a prescription for oral anticoagulants for outpatient use.

Resumo O objetivo deste artigo é relatar o caso de um homem de 53 anos de idade, negro, sem comorbidades prévias, com diagnóstico confirmado de COVID-19 há 48 dias anteriores ao início do quadro de dor epigástrica insidiosa, que evoluiu para dor de forte intensidade que irradiava para região interescapulovertebral, associada a hiporexia e episódios de vômitos em jato, sem náuseas ou febre. Os exames laboratoriais não apresentavam sinais de infecção aguda ou lesão pancreática. A tomografia computadorizada do abdome mostrou alças do intestino delgado dilatadas, cheias de líquido e com paredes espessas. Após terapia de suporte, o paciente evoluiu com dor abdominal persistente. Foi realizada laparotomia exploratória, na qual foram encontrados dois sítios de estenose no intestino delgado sem causa extrínseca, ao lado de sinais de isquemia local e distensão importante das alças jejunais e ileais. Após enterectomia e enteroanastomose primária látero-lateral, o paciente evoluiu de forma satisfatória e recebeu alta hospitalar com prescrição de anticoagulantes orais para uso ambulatorial.

Avaliação do nível de conhecimento em relação à Aids e sífilispor idosos do interior cearense, Brasil / Evaluation of the level of knowledge about Aids and syphilis among the elderly from a city in the interior of the state of Ceará, Brazil

Resumo O propósito deste trabalho foi avaliar o conhecimento de idosos acerca da sífilis e Aids antes e após a realização de ações educativas. Foram selecionados 55 idosos que participavam de grupo de conveniência no território dos Terrenos Novos, em Sobral - CE. Para a coleta dos dados, utilizou-se um questionário semiestruturado sobre HIV/Aids e sífilis, incluindo características gerais e informações sobre conceito, transmissão, prevenção, vulnerabilidade e tratamento. O questionário foi aplicado antes e após a realização de oficinas educativas sobre Aids e sífilis. Dentre os investigados, 96,4%, tinham conhecimento sobre Aids e 67,3% desconheciam a sífilis. Entretanto, 38,1% acreditavam que beijo na boca e 78,1% que picada de mosquito eram meios de transmissão do HIV. Desconheciam a forma de transmissão da sífilis 70,9%. Após as oficinas os índices alteraram positivamente. A análise dos dados revelou lacunas no conhecimento deste grupo quanto ao conceito, transmissão e tratamento dessas doenças. As intervenções educativas mostraram-se eficazes para a assimilação de conhecimento.

Abstract The scope of this study was to evaluate the knowledge of the elderly about syphilis and AIDS before and after conducting educational activities. Fifty-five individuals participating in a convenience group from territory of Terrenos Novos in Sobral in the State of Ceará were selected. To collect the data, a semi-structured questionnaire about HIV/AIDS and syphilis was used, including general features and information about concept, transmission, prevention, vulnerability and treatment. The questionnaire was applied before and after the implementation of educational workshops about AIDS and syphilis. Among those surveyed, 96.4% were aware about AIDS and 67.3% did not know about syphilis. However, 38.1% believed that a kiss on the mouth and 78.1% that mosquito bites were means of HIV transmission. 70.9% did not know the mode of transmission of syphilis. After the workshops the indexes changed positively. Data analysis revealed gaps in knowledge of this group about the concept, transmission and treatment of these diseases. Educational interventions were effective for knowledge assimilation.

Occurrence and antimicrobial susceptibility of enteric rods and pseudomonads isolated from the dental prostheses biofilm

ABSTRACT Aspiration of oral bacteria leads to cardiac and respiratory infectious diseases and dentures can act as a reservoir for pathogenic microorganisms. Objective: To determine the occurrence and the in vitro antimicrobial susceptibility of enteric rods and pseudomonads from the denture biofilm of 52 subjects at the Center for Dental Specialties of Sobral/ Ceara, Brazil. Material and Methods: Denture biofilm was collected and samples plated on MacConkey agar. The isolated bacterial colonies were identified using the BBL Crystal enteric/non-fermenter system. Antibiotic bacterial susceptibility was assessed by the disc diffusion method of amoxicillin, amoxicillin/clavulanic acid, doxycycline, tetracycline, tobramycin, imipenem, cefotaxime, and ciprofloxacin. The Minimum Inhibitory Concentration (MIC) of cefotaxime, tobramycin, doxycycline, imipenem, and ciprofloxacin was determined for 40 species by E-test. Results: 34 subjects (65.4%) harbored enteric rods in their prostheses. Klebsiella pneumoniae (26.5%), Escherichia coli (23.5%), and Enterobacter aerogenes (23.5%) were the most prevalent species. All organisms were susceptible to ciprofloxacin and most species were resistant to amoxicillin or amoxicillin/clavulanic acid, demonstrating variable sensitivity patterns to other antimicrobials. However, the MIC showed the emergence of strains with reduced sensitivity to ciprofloxacin (MIC90≥3 μg/ mL) and cefotaxime (MIC90≥2 μg/mL). Conclusion: The findings show high prevalence of nosocomial diseases-related bacterial species and low susceptibility to antimicrobial drugs. Therefore, these results imply caution against the indiscriminate use of broad spectrum antibiotics in dental practice.