Role of Mean Platelet Volume in Ischemic Stroke.

The present study was done to study the role of Mean platelet volume in the pathogenesis,severity and outcome of ischemic stroke. The present prospective study comprised of 100 patients each of ischemic stroke with equal number of age and sex matched control group.Modified Rankin scale was used to assess the severity of stroke.Mean platelet volume and platelet count were lower and higher in the control group.PDW and PLCR were higher in the study group.57% stroke patients were independent at the end of first week.Patients with high Mean platelet volume did worse at the end of first week in comparison to the control group(p value=<0.05). Mean platelet volume bears an inverse relationship to the immediate outcome from ischemic stroke independent of stroke subtype.

Haemophilic Arthropathy

Bleeding into joints and soft tissues are the hallmark of haemophilia. The severity of manifestations co-relates with deficiency of the factor. The resorption of intra-articular blood induces reactive synovitis and causes cartilage damage, finally causing complete destruction of it. We hereby report a similar case and highlight various rheumatic manifestations of haemophilia and its management.