Study Of Radiological Evaluation Of Cervical Spine In Marathwada Region

Background:Cervical vertebraeare the most crucially located and play a dynamic role in the mobility and protection of the vital parts of the central nervous system, they are prone to undergo degenerative diseases like spinal stenosis, cervical spondylosis etc.Hence it is important to know the exact dimensions of cervical vertebralbody and spinal canal in the diagnosis, prognosis and treatment of diseasesrelated tocervical spine and spinal cord.Material And Methods:Normal plain radiographs of cervical spine of two hundred adult subjects of known sex (one hundred males and one hundred females) and of known age group (between 18 to 50 years) studied for Antero-posterior diameter of vertebral body (AP-VB), Height of vertebral body (HT-VB)and Canal body ratio (CBR) in C3 to C7 cervical vertebrae. Data tabulated and analysed by using software statistical Package for Social Sciences(SPSS).Result:Higher mean AP –VB diameter andmean Ht -VB valuesare recorded in males as compared to females.Highermean Canal body ratio (CBR) was recorded in femalesascompared to males.Conclusion:Present study showed,higher mean value of(AP-VB),(HT-VB) in males as compared to females and found to be statistically significant indicating sexual dimorphism. Canal body ratio(CBR) showed slightly higher values in females as compared to malesand found statistically significant at C6 and C7 Levels.

Increased free radical activity in burns.

In burn trauma there is excessive activity of FR at the site of injury that result in oxidative stressful state. This is reflected as elevated blood levels of LPP, UA and CLP. The fall of AA in serum appears to counteract the oxidative stress. Increased eCAT activity occurs as a metabolic response to compensate the oxidative stress. These alterations in the biochemical parameters occur parallel to the degree of burn injury. It is suggested that therapeutic use of antioxidants may be beneficial in the clinical management of burn patients.

Relationship of erythrocyte superoxide dismutase, serum lipid peroxides and age.

Serum Lipid peroxides (LP) were measured as an index of free radical mediated lipid peroxidation in sixty normal healthy individuals. Erythrocyte superoxide dismutase (SOD) activity was also measured simultaneously in the subjects. The serum LP levels were found to be increased progressively with age, while erythrocyte SOD was, in contrast, found to be decreased with age. There was excellent positive correlation between serum LP and age (r = 0.959) while the erythrocyte SOD was inversely correlated with age (r = -0.845). The serum LP and erythrocyte SOD have also shown some inverse relationship (r = -0.8395). The result indicate that the balance between antioxidant & pro-oxidant factors in free radical metabolism shifts towards increased lipid peroxidation with advancing age.

Determination of gestational age of newborns--a comparative study.

Four hundred newborns were evaluated to study a clinical method for assessment of gestational age which is simple, accurate and is within scope of those who are not trained in pediatrics. Gestational age was estimated by three methods, namely, the last menstrual period of mother, Dubowitz method, and a simple clinical method devised by us. Dubowitz's method was marginally superior than our method in estimating the gestational age correctly; but out method was simpler, less time consuming and less disturbing to the baby. The relation between the total score and gestational age in weeks was observed to be non-linear.