Sujets)
Infections communautaires/microbiologie , Infections communautaires/anatomopathologie , Résistance microbienne aux médicaments/épidémiologie , Humains , Staphylococcus aureus résistant à la méticilline/analyse , Infections cutanées à staphylocoques/analyse , Infections cutanées à staphylocoques/épidémiologie , Infections cutanées à staphylocoques/anatomopathologie , Infections des tissus mous/analyse , Infections des tissus mous/épidémiologie , Infections des tissus mous/anatomopathologieRésumé
BACKGROUND AND PURPOSE: Resistance to fluoroquinolones and cephalosporins is a major problem with Salmonella enterica serovar Typhi and Paratyphi. An accurate determination of antibiotic susceptibility requires tests for minimum inhibitory concentration (MIC) of antibiotics. We describe a simple broth-disk method to determine the MIC of ceftriaxone on S. typhi and S. paratyphi. MATERIALS AND METHODS: Sixteen strains of S. typhi and two strains each of S. paratyphi A and S. paratyphi B were used in the study. The MIC of ceftriaxone was determined using the simple broth-disk method and the conventional broth macrodilution method and the results were compared. RESULTS: All salmonella strains were susceptible to ceftriaxone. The results of the broth-disk and the conventional broth macrodilution method were similar. CONCLUSION: The broth-disk method is a simple, reliable and cost-effective method to determine the MIC of ceftriaxone on S. typhi and S. paratyphi A.