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Rev. Soc. Bras. Med. Trop ; 47(4): 528-532, Jul-Aug/2014. tab, graf
Article Dans Anglais | LILACS | ID: lil-722305

Résumé

Urinary symptoms occur in 19% of human T-cell lymphotropic virus type 1 (HTLV-1)-infected patients who do not fulfill criteria for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and in almost 100% of HAM/TSP patients. Few studies have evaluated therapies for overactive bladder (OAB) caused by HTLV-1 infection. This case report describes the effect of onabotulinum toxin A on the urinary manifestations of three patients with HAM/TSP and OAB symptoms. The patients were intravesically administered 200 units of Botox®. Their incontinence episodes improved, and their OAB symptoms scores (OABSS) reduced significantly. These data indicate that Botox® should be a treatment option for OAB associated with HTLV-1 infection.


Sujets)
Femelle , Humains , Adulte d'âge moyen , Jeune adulte , Inhibiteurs de la libération d'acétylcholine/usage thérapeutique , Toxines botuliniques de type A/usage thérapeutique , Paraparésie spastique tropicale/complications , Vessie hyperactive/traitement médicamenteux , Résultat thérapeutique , Vessie hyperactive/virologie
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