Résumé
Background: Acute Kidney Injury (AKI) increases morbidity, mortality and hospital stay in critical patients units (CPU). Aim: To determine the incidence and mortality of AKI in CPU. Material and Methods: Review of electronic medical records of 1,769 patients aged 61 ± 20 years (47% males) discharged from a CPU during one year. Acute Kidney Injury diagnosis and severity was established using the Acute Kidney Injury Network (AKIN) criteria. Results: A history of hypertension and Diabetes Mellitus was present in 44 and 22% of patients, respectively. APACHE II and SOFA scores were 14.6 ± 6.8 and 3.6 ± 2.1 respectively. AKI incidence was 28.9% (stage I, 16.7%, stage II, 5.3% and stage III, 6.9%). Mortality during the first 30 days and during the first year was 8.1 and 20.0% respectively. Patients with stage III AKI had the highest mortality (23.8 and 40.2% at 30 days and one year respectively). Compared with patients without AKI, the Odds ratio for mortality at 30 days and one year of patients with AKI stage III was 3.7 and 2.5, respectively. Conclusions: Thirty percent of patients admitted to UPC develop an AKI, which influences 30 days and one year mortality.
Sujets)
Adulte , Sujet âgé , Sujet âgé de 80 ans ou plus , Femelle , Humains , Mâle , Adulte d'âge moyen , Atteinte rénale aigüe/mortalité , Unités de soins intensifs/statistiques et données numériques , Centres de soins tertiaires/statistiques et données numériques , Atteinte rénale aigüe/épidémiologie , Diabète/mortalité , Mortalité hospitalière , Hospitalisation/statistiques et données numériques , Hypertension artérielle/mortalité , Incidence , Pronostic , Études rétrospectives , Appréciation des risquesRésumé
Las glomerulonefritis (GN) son enfermedades caracterizadas por inflamación glomerular y proliferación celular, asociada a hematuria. Los mecanismos inmunes humorales y los mediados por células, juegan un papel importante en la patogenia de la inflamación glomerular. La enfermedad glomerular tiende a producir síndromes de disfunción renal específica. Sin embargo, diferentes enfermedades glomerulares pueden producir síndromes semejantes. En este trabajo se revisa la fisiopatología, la historia natural y el tratamiento de la hematuria asintomática, la glomerulonefritis aguda y la glomerulonefritis rápidamente progresiva.