Identification of the types of human papillomavirus in condylomata acuminata using polymerase chain reaction / 대한피부과학회지

Polymerase chain reaction was performed to determine he types of human papillomavirus (HPV) causing condylomata acuminata in frozen tissues and paraffinembedded tissues of condylomata acuminata. HPV DNA was detected in 31 of 32 patients with condylomata aciminata. HPV 6 and/or 11, low-risk types in genital carcinogenesis, were present in all cases in whieh HPV was detected. Both types were present in 5 cases. It is, therefore, supposed that there is not much risk of this disease to transform to the invasive cancer in Korean and polymerase chain reaction can be used to deteet HPV and identify its type from paraffin-embedded tissues.