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Acta cient. venez ; 47(3): 172-7, 1996. tab
Article Dans Espagnol | LILACS | ID: lil-217147

Résumé

In the present study we measured the activities of the following enzymes: LDH (lactic dehydrogenase), beta-glucuronidase, acid maltase, phosphohexoseisomerase (PHI) and acid proteases in the gastric juice of patients with gastric cancer (n = 50) (Case Group), in endoscopically normal subjects (n = 50) and in subjects with different non tumor-like digestive pathologies (n = 55) (Control Groups). In the patients with gastric carcinoma we found a significant increase in LDH, beta-glucuronidase, PHI and acid maltase activities and a decreased activity of acid proteases. The results agree with previous findings from other workers. The variations of enzyme activities in gastric juice can help to differentiate between malignant and benign processes of the gastric mucosa.


Sujets)
Humains , Mâle , Femelle , Adulte , Adulte d'âge moyen , Adénocarcinome/diagnostic , Tests enzymatiques en clinique , Tumeurs de l'estomac/diagnostic , Suc gastrique/enzymologie , Sujet âgé de 80 ans ou plus , Analyse de variance , Études cas-témoins , Glucose 6-phosphate isomerase/métabolisme , Glycosidases/métabolisme , L-Lactate dehydrogenase/métabolisme
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