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China Journal of Chinese Materia Medica ; (24): 609-611, 2002.
Article Dans Chinois | WPRIM | ID: wpr-271862

Résumé

<p><b>OBJECTIVE</b>To observe the effect of the crude extracts of Dan-shen root and San-qi of different proportion on platelet aggregation and adhesion in normal rabbits.</p><p><b>METHOD</b>With rabbits, ig. (4d, exsanguinated via carotid artery, percentage of platelet aggregation and adhesion was measured.</p><p><b>RESULT AND CONCLUSION</b>Aspirin (4.4 mg/Kg) could markedly inhibit platelet aggregation and adhesion in normal rabbit. The proportions of Dan-shen root/San-qi (10:0, 10:1, 10:3, 10:6, 1:10) could markedly inhibit platelet aggregation, among which 10:3 was the best. San-qi alone had little effect on aggregation. The proportions of Dan-shen root/San-qi (10:3, 10:6, 0:10) could markedly inhibit platelet adhesion, among which 0:10 was the best, and the proportions(10:0, 10:1, 1:10) had little effect.</p>


Sujets)
Animaux , Femelle , Mâle , Lapins , Association médicamenteuse , Médicaments issus de plantes chinoises , Pharmacologie , Panax , Chimie , Racines de plante , Chimie , Plantes médicinales , Chimie , Adhésivité plaquettaire , Agrégation plaquettaire , Antiagrégants plaquettaires , Pharmacologie , Salvia miltiorrhiza , Chimie
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