Résumé
Abstract Objective: Evaluate histological changes in testicular parameters after hormone treatment in transgender women. Methods: Cross-section study with patients who underwent gonadectomy at Hospital de Clínicas de Porto Alegre from 2011 to 2019. Hormone treatment type, route of administration, age at initiation and duration were recorded. Atrophy parameters were observed: testicular volume, tubular diameter, basal membrane length, presence of spermatogonia and spermatids (diploid and haploid spermatozoid precursors). Results: Eighty-six patients were included. Duration of hormone treatment is associated with testicular atrophy and spermatogenesis arrest. Other characteristics of hormone treatment such as age of initiation, route of administration and type of treatment were not associated with testicular histological changes. Testicular volume may predict spermatogenesis arrest. Basal membrane length and tubular diameter ratio is an interesting predictor of germ cell presence. Conclusion: Cross-sex hormone treatment affects testicular germ cell presence. Basal membrane length and tubular diameter ratio reduces inter variability of measurements and better exemplify how atrophic seminiferous tubules are. Fertility preservation should be addressed by healthcare providers in order to recognize gender affirming treatment impact on transgender health.
Résumé
O estudo de hábitos orais é muito realizado na infäncia, entretanto na adolescência este assunto tem sido pesquisado, mesmo com o conhecimento de que hábitos podem ter consequências nocivas nesta faixa etária. O presente estudo teve o objetivo de verificar, através de entrevista individual, a ocorrência de hábitos orais em 83 adolescentes, de 15 a 17 anos, residentes em Camaquä, RS. Os resultados mostraram que os hábitos orais sä muito comuns nesta faixa etária, atingindo 96 por cento da populaçäo adolescente estudada. Os hábiotos referidos relacionaram-se principalmente com os de mastigaçäo, suçäo e mordida, e apresentaram-se associados em sua maioria, dado que indica a necessidoade de novos estudos que verifiquem a influência destes nesta idade.