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Rev. Soc. Bras. Med. Trop ; 53: e20190583, 2020. tab, graf
Article Dans Anglais | SES-SP, ColecionaSUS, LILACS | ID: biblio-1136797

Résumé

Abstract INTRODUCTION: We performed an epidemiological surveillance of the Chikungunya (CHIKV) lineages in Bahia after the 2014 East/Central/South African (ECSA) genotype outbreak. METHODS: Reverse-transcription polymerase chain reaction (RT-PCR), viral isolation, and phylogenetic analyses were conducted on serum samples from 605 patients with CHIKV-like symptoms during 2014-2018. RESULTS: Of the 605 samples, 167 were CHIKV-positive. Viral isolation was achieved for 20 samples; their phylogenetic analysis (E2 protein) revealed the presence of ECSA lineage and reinforced the phylogenetic relationship between ECSA and Indian Ocean lineages. CONCLUSIONS: The genomic surveillance of CHIKV showed that only ECSA lineage circulated in Bahia since the 2014 outbreak.


Sujets)
Humains , Mâle , Femelle , Adulte , Virus du chikungunya/génétique , Génome viral/génétique , Fièvre chikungunya/virologie , Phylogenèse , Brésil/épidémiologie , Épidémies de maladies , RT-PCR , Surveillance épidémiologique , Fièvre chikungunya/épidémiologie , Génotype
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