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1.
Rev. méd. Chile ; 124(7): 813-9, jul. 1996. ilus, tab, graf
Article Dans Espagnol | LILACS | ID: lil-174908

Résumé

Adult respiratory distress syndrome is highly prevalent in intensive care units and has a high mortality. Lately, nitric oxide has been used as adjuvant therapy. To study the effects of nitric oxide inhalation in patients with adult respiratory distress syndrome, 12 patients were subjected to nitric oxide inhalation at a concentration of 10 parts per million, during 30 minutes. At the end of the nitric oxide inhalation period, there was an improvement of PaO2/FIOa ratio from 89ñ32 to 111ñ43 mm Hg and 16 percent reduction of lung shunting (Qs/Qt). Nitric oxide inhalation at a concentration of 10 parts per million improved arterial oxygenation and reduced pulmonary shunting in patients with adult respiratory distress syndrome


Sujets)
Humains , Mâle , Femelle , Adulte , Adulte d'âge moyen , Monoxyde d'azote/pharmacocinétique , /thérapie , Thérapie respiratoire , Échanges gazeux pulmonaires/physiologie , Hémodynamique , /physiopathologie
2.
Rev. méd. Chile ; 124(1): 94-102, ene. 1996. tab, graf
Article Dans Espagnol | LILACS | ID: lil-173310

Résumé

Inhalation therapy with nitric oxide has been suggested as beneficial in the adult respiratory distress syndrome, however there are few reports of its prolonged use. We report a patient with a chronic lymphocytic leukemia that developed an adult respiratory distress syndrome with severe hypoxemia, refractory to conventional therapeutic measures, during the course of a septic shock. The patient received nitric oxide (19 ppm) improving arterial oxygen saturation and allowing the reduction of FiO2 to 40 percent. The patient died 5 days later due to a multiple organ failure


Sujets)
Humains , Mâle , Sujet âgé , Monoxyde d'azote/administration et posologie , /thérapie , Hémodynamique , Leucémie lymphoïde/complications , Pression sanguine , Choc septique/complications
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