Effect of raloxifene on alveolar bone resorption after mucoperiosteal fl ap surgery in mice / Efeito do raloxifeno sobre reabsorção óssea alveolar após cirurgia de retalho mucoperiosteal em camundongos

Background: Mucoperiosteal fl ap surgeries (MFS) are carried out to provide access to the alveolar bone and root surfaces in several clinical situations. Nevertheless, they lead to a variable degree of alveolar bone resorption. Raloxifene is an agonist in bone, and acts inhibiting bone loss. Objective: To evaluate the effect of raloxifene in preventing alveolar bone resorption after MFS using an experimental model of mouse mandibles. Methods: MFS was performed on the buccal aspect of the left side of the mandible (BL) in 20 male CF1 Musdomesticus mice divided into two groups with the same number of animals: the experimental group was treated once daily with raloxifene injections (3 mg/kg), and the placebo group was treated with daily injections of the vehicle. The buccal aspects of right hemimandibles were used as controls (BR). Mandibles were removed, defl eshed and stained with toluidine blue in a stereomicroscope. Digital images were obtained and the alveolar bone loss was measured (mm²) using an image analysis software. Results: The BL area exhibited signifi cantly more bone loss (Student t test; p < 0.01) when compared to the BR area, in both groups. No statistically signifi cant difference was observed between the experimental and the placebo groups. Conclusion: In this study, raloxifene did not inhibit alveolar bone resorption following MFS in male mice.

Introdução: Cirurgias de retalho mucoperiosteal (CRM) são realizadas para permitir acesso ao osso alveolar e à superfície radicular em várias situações clínicas. No entanto, elas levam a um grau variável de reabsorção óssea alveolar. O raloxifeno tem ação agonista em tecido ósseo e atua inibindo perda óssea. Objetivo: Avaliar o efeito do raloxifeno na prevenção de reabsorção óssea alveolar após CRM usando o modelo experimental de mandíbulas de camundongos. Métodos: Foram realizadas CRMs na face vestibular, lado esquerdo, das mandíbulas (VE) de 20 camundongos CF1 Musdomesticus machos, divididos em dois grupos com mesmo número de animais: o grupo experimental foi tratado uma vez ao dia com injeções de raloxifeno (3 mg/kg), e o grupo placebo foi tratado uma vez ao dia com injeções do veículo. A face vestibular do lado direito da hemimandíbula foi usada como controle (BD). As mandíbulas foram removidas, dissecadas e coradas com azul de toluidina sob um estereomicroscópio. Imagens digitais foram obtidas e a perda óssea alveolar foi medida (mm²) usando um software de análise de imagens. Resultados: A área VE exibiu perda óssea signifi cativamente maior (teste t de Student; p < 0,01) quando comparada com a área BD, em ambos os grupos. Não foi observada diferença estatisticamente signifi cativa entre os grupos experimental e placebo. Conclusão: Neste estudo, o raloxifeno não inibiu a reabsorção óssea alveolar após CRM em camundongos machos.

Odontologia e qualidade de vida: uma abordagem baseada em evidências / Dentistry and quality of life: an evidence-based approach

A qualidade de vida é um dos temas bastante ressaltados na contemporaneidade. O aumento da expectativa de vida e o incremento do cuidado em saúde geraram exigências para que a vida seja cada vez mais repleta de qualidade. Nesse sentido, houve popularização excessiva de terminologia “qualidade de vida”. Não há dúvida de que é importante que haja o entendimento da população sobre a importância de viver com qualidade. Entretanto, as abordagens em saúde que procuram avaliar impactos na qualidade de vida necessitam ser trabalhadas de forma mais profunda, e não simplesmente no nível da hipótese e do senso comum. Não se pode achar que é óbvio que todo cuidado bucal impacte positivamente na qualidade de vida. Essa informação necessita estar embasada em estudos de qualidade. Assim, muitos instrumentos e formas sistemáticas de avaliação de qualidade de vida relacionada à saúde bucal foram desenvolvidos, o que permite que essa temática seja trabalhada à luz da literatura. O objetivo desta coluna é fazer uma análise do impacto da saúde bucal na qualidade de vida, demonstrando a importância da profissão para melhorá-la...

Quality of life is one of the contemporary hot topics. The increased life expectancy, along with the improved health care have generated demands for a life full of quality. As a consequence, the expression “quality of life” has been excessively used. There is no doubt that it is important for the populations to understand the importance of living with quality. However, health care approaches towards the evaluation of impact in quality of life need to be studied deeper, not only in the hypothetical but in the common sense level. It is not fair to consider obvious that every oral care measure impacts positively in quality of life. This information needs to be based in high quality studies. Thus, several instruments and systematic approaches for evaluating oral health related to quality of life have been developed, allowing for this theme to be addressed in the light of the current literature. The aim of this paper is to analyze the impact of oral health on quality of life, demonstrating the importance of the profession for its improvement...

Measurement of loosening torque of prosthetic components in Morse taper connection implants

AIM: The aim of this study was to verify two different types of interfaces in Morse taper connection implants, relating the mechanical resistance to a loosening torque that is required to separate or move the prosthetic abutment. MATERIAL AND METHODS: Ten Morse taper connection implants and their respective abutments were divided into two groups (n = 5), DH (double hexagon) interface and OI (octagonal implant) interface. A standard insertion of implants was performed in a stainless steel base, where each abutment received a sequence of two consecutive tightening torques at a 10-minute interval, followed by a loosening torque, which was measured using a digital torque gauge. The Student's t-test with a 5% significance level was used for data analysis. RESULTS: The results showed a statistically significant difference in the loosening torque values compared with DH torque values (p < 0.05). However, the difference between tightening and loosening torque values was not statistically significant in the OI group (p = 0.465). CONCLUSION: The study concluded that there was a difference in the torque required to loosen the abutment screws between the DH group and the OI group, with the latter showing better results.

Food intake selection influenced by opposing functional natural teeth or removable denture: observational study

AIM: The purpose of this study was to investigate the relationship between types of dentition in occlusion and the perceived ability to eat a range of common foods in elderly. MATERIAL AND METHODS: We included 363 individuals (117 men, 246 women; mean age = 73.4 ± 5.8 years) Self-reported information on questionnaires were linked to oral examination to establish types of dentition in occlusion assessing their influence on the needs to alter the food selection and on the difficulty to chew key foods. RESULTS: The individuals were classified as having their occlusion performed by completed removable prostheses (D/D) (51.2%), mixed dentition (D/N-N/D) (32.8%) or with natural teeth (N/N) (16%). Individuals with natural teeth N/N or mixed dentition (N/D-D/N) had less necessity to change their food intake, relative to individuals with their occlusion performed by complete removal denture (D/D) (p<0.05). Most of the individuals that had to modify their food intake avoided hard-to-chew food (p<0.05). CONCLUSION: The reduced masticatory ability may lead to changes in dietary selection with risk of an impaired nutritional status especially in elderly complete denture wearers.