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1.
Neurol India ; 2003 Dec; 51(4): 525-7
Article Dans Anglais | IMSEAR | ID: sea-120243

Résumé

Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare, recently described disease. It is characterized clinically by a large head, mild neurological symptoms and a remarkably slow course of functional deterioration. The MRI is characterized by 'swollen white matter' and large symmetrical cystic changes in the cerebral hemispheres. MLC should be considered in the differential diagnosis of children with megalencephaly and leukoencephalopathy. We report a child with this disease and discuss the MRI and MRS features.


Sujets)
Noyaux gris centraux/anatomopathologie , Kystes du système nerveux central/anatomopathologie , Humains , Nourrisson , Imagerie par résonance magnétique , Spectroscopie par résonance magnétique , Mâle , Mésencéphale/anatomopathologie
2.
Neurol India ; 2002 Sep; 50(3): 282-5
Article Dans Anglais | IMSEAR | ID: sea-121026

Résumé

Intracranial metastases of central nervous system are relatively common in patients with systemic cancer. Computed tomography (CT) scans of 60 patients of intracranial metastatic disease of unknown primaries, at the time of surgery, were retrospectively analyzed. These patients primarily presented with neurological dysfunction. They were operated upon for various reasons and histopathological diagnosis was obtained. There were 39 male and 21 female patients, with age range of 18 to 74 years. The common clinical symptoms were raised intracranial pressure without lateralization, acute onset hemiplegia and seizures. Multiple cranial nerve palsies were observed in 4 patients. Histopathologically the intracranial lesions consisted of metastatic adenocarcinoma (32 cases) or metastatic squamous cell carcinoma (28 cases). Among cases of adenocarcinoma, CT revealed solitary lesions in 17 and multiple lesions in 13 cases. Two had extraaxial deposition in the region of petrous apex. Out of squamous cell carcinomas, 17 lesions were solitary, while 10 were multiple and one had extraaxial deposition in the region of petrous apex. This study is unique as it consisted of CT features of intracranial metastases of unknown primary malignant disease elsewhere in the body.


Sujets)
Adénocarcinome/imagerie diagnostique , Adolescent , Adulte , Sujet âgé , Tumeurs du cerveau/imagerie diagnostique , Carcinome épidermoïde/imagerie diagnostique , Femelle , Humains , Mâle , Adulte d'âge moyen , Métastases d'origine inconnue/anatomopathologie , Tomodensitométrie
3.
Neurol India ; 2002 Sep; 50(3): 310-2
Article Dans Anglais | IMSEAR | ID: sea-120954

Résumé

A 56 year old man presented with acute onset posterior column and lateral spinothalamic tract dysfunction over a period of 15 days. MRI showed diffuse hyperintensity on T2WI involving the posterior columns. A diagnosis of subacute combined degeneration (SCD) of the spinal cord was considered and confirmed by laboratory findings. The patient showed complete recovery on B12 therapy. MRI lesion also compeletely resolved.


Sujets)
Humains , Imagerie par résonance magnétique , Mâle , Adulte d'âge moyen , Moelle spinale/anatomopathologie , Maladies de la moelle épinière/étiologie , Carence en vitamine B12/complications
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