A Study To Assess Acute Physical Reactions Experienced By First Year Medical Students On Exposure To Formaldehyde During Gross Anatomy Dissection

Medical students are exposed to formaldehyde regularly during gross anatomy dissection classes as the cadavers are embalmed with formalin, which on vapourization yields formaldehyde. They develop various physical reactions, most commonly irritation of mucosal surfaces of the nose, eyes and throat. The present study was done to evaluate these symptoms and how they change longitudinally over one month of exposure. Descriptive statistics and Wilcoxon signed rank test were applied for analysis. A p–value < 0.05 was considered significant. High incidence of eye and nasal irritation was noted along with a few others. After one month, a significant decline in throat irritation, unpleasant odour, nausea and headache was observed, while in others the decrease was non–significant. The wide spectrum of physical reactions demonstrates the detrimental effect of formaldehyde in the body. We should therefore ensure reduction of exposure by use of protective goggles, masks, improving ventilation and preventing unnecessary spillage of the formalin within the dissection hall.

Study of FEV1/FVC Ratio In Relation to BMI in Young Group of Rohilkhand Region.

Background: The aim of study was to to assess respiratory indices in underweight and overweight young group (subcategory) and compare the same with normal weight controls (in the age group of 18 to 30 years). Methods: In the present study 210 subjects were included, aged between 18 yrs-30 yrs after applying inclusion and exclusion criteria. The groups (n=210, case= 132 and control= 78) are divided into group A, B, C, D, E and F respectively each having 21, 78, 40. 35, 29 and 7 subjects on the basis Of international classification of BMI. Results: In our study mean predicted value of FEV1/FVC ratio in group A 84.02±31.24(underweight), group C 86.83±29.46(pre-obese), group D 92.10±13.31(obese class 1),group 93.72±9.49 ( obese class 2) and group F191.02±22.24( obese class 3), when compared to control group B 87.95±26.77 was found to be decreased in group A and increased in other obese group , but it was within normal range in all groups and no statistical difference found between different groups (P value>0.05). Conclusion: After analyzing the data, we did not observe any statistically significant difference in FEV1/FVC between the control and underweight and overweight group.

Study of Blood Pressure and Heart Rate Variability in Office Clerks.

Background: hypertension is prevalent worldwide especially in young generation is a significant.it is associated with the development of autonomic and metabolic disorders. Hypertension is often found in high stress work situations. The present study was undertaken to compare the arterial blood pressure (BP) and Heart Rate Variability (HRV) in office clerks. Methods: Seventy four male clerks of various offices in Bareilly, U.P., India. The age group of subjects was 21–50 years. They were divided into two groups based on their BP recordings. 21 were normotensives and 53 hypertensive. Anthropometric measurements and their BP in supine position were recorded. Deep breathing HRV test was conducted. HRV levels were compared statistically between the two groups. Results: The Hypertensive had significantly lesser HRV (p=0.027) compared to normotensives. Conclusion: Hypertensive office clerks have lower heart rate variability. Blood pressure is inversely proportional to heart rate variability.

Effect of Pranayama on Respiratory Parameters in Aged Person.

Background: Body and mind work perfectly after yoga. To find out the effect of yoga (pranayama) on respiratory parameter a cross sectional study was conducted. Methods: Subjects selected are people (male and female) aged from 50-70 year without any active medical complain. Study is conducted in RMCH Bareilly U.P. Results: Respiratory parameters measured are FVC, FEV1, ratio of FVC/FEV1 and PEFR. These parameters are taken before and after 12 week of pranayama. Conclusion: 12 weeks of regular yogic training in elderly individuals showed definite improvement in their ventilatory functions, as observed from improvement in their FVC, FEV1 FEV1/FVC RATIO and PEFR.