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Int. braz. j. urol ; 44(6): 1147-1155, Nov.-Dec. 2018. tab, graf
Article de Anglais | LILACS | ID: biblio-975654

RÉSUMÉ

ABSTRACT Objective: To investigate the relationship between the pretreatment body mass index (BMI) and the clinical outcomes in patients with localized stage I - III renal cell carcinoma (RCC) surgically treated. Materials and Methods: From January 2000 to December 2012, 798 patients with stage I - III RCC were recruited from First Affiliated Hospital and Cancer Center of Sun Yat - Sen University. Patients were divided into two groups of BMI < 25 kg / m2 or BMI ≥ 25 kg / m2 according to the World Health Organization classifications for Asian populations. The differences in the long-term survival of these two BMI groups were analyzed. Results: The 5 - year failure - free survival rates for BMI < 25 kg / m2 and BMI ≥ 25 kg / m2 groups were 81.3% and 93.3%, respectively (P = 0.002), and the 5 - year overall survival rates were 82.5% and 93.8%, respectively (P = 0.003). BMI was a favored prognostic factor of overall survival and failure - free survival in a Cox regression model. Conclusions: Pretreatment body mass index was an independent prognostic factor for Chinese patients surgically treated, localized stage I - III RCC.


Sujet(s)
Humains , Mâle , Femelle , Adulte , Sujet âgé , Sujet âgé de 80 ans ou plus , Néphrocarcinome/mortalité , Indice de masse corporelle , Tumeurs du rein/mortalité , Pronostic , Néphrocarcinome/chirurgie , Néphrocarcinome/anatomopathologie , Taux de survie , Études rétrospectives , Tumeurs du rein/chirurgie , Tumeurs du rein/anatomopathologie , Adulte d'âge moyen , Stadification tumorale
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