Résumé
Objective To observe the OCT image characteristics of the posterior cortical anterior vitreous capsular bag (PPVP) in human eyes.Methods A retrospective clinical study.From May 2012 to February 2017,107 PPVP patients (173 eyes) diagnosed by OCT in Ophthalmology Department of The Third People's Hospital of Chengdu were included in the study.One hundred and three eyes underwent examination of frequency-domain OCT (SD-OCT) and 70 eyes underwent examination of frequency-scanning light source OCT (SS-OCT),respectively.SD-OCT the German Heidelberg Spectralis OCT instrument.SS-OCT was performed by the vitreous enhancement scan mode of Japan's Topcon DRI OCT instrument.The differences of different types of PPVP OCT imaging and image characteristics were observed.Results SD-OCT and SS-OCT showed that the PPVP structure was clear and manifested as macular weakly reflective in the shape of a boat-shaped cavity,the front boundary was vitreous collagen,and the rear boundary was vitreous cortex.There was a weakly reflective Martegiani area on the nasal side of PPVP,and there was a connection channels between them.The two examinations showed a similar pattern,but SS-OCT with the clearer imaging of PPVP.Conclusions The OCT image of PPVP in the human eye is characterized by an anterior weakly reflecting boat-shaped cavity in the macula,with anterior border of vitreous collagen and posterior border of vitreous cortex.Martegiani area is located on the nasal side.
Résumé
AIM: To investigate the antitumor activity and mechanism of Paecilomyces tenuipes polysaccharide(PTPS).METHODS: PTPS-I was obtained by water extraction and alcohol precipitation,and purified by DEAE-cellulose and Sephadex G-100 chromatography.Human erythroleukemia cell line K562,laryngocarcinoma cell line Hep2 and hepatic carcinoma cell line SMMC-7721were co-cultured with PTPS-I or the conditioned medium which prepared with PTPS-I-stimulated human mononuclear cells(PTPS-I-MNC-CM),and the proliferation of tumor cells was determined.The cell counting kit-8(CCK-8) was used to determine the proliferation of MNCs.The FQ-RT-PCR was applied to investigate the expression of TNF-? and IL-6 mRNA in MNCs.RESULTS: PTPS-I-MNC-CM inhibited the proliferation of K562,Hep2 and SMMC-7721 cells in vitro(P