RÉSUMÉ
Objective@#To explore the life quality of decompensated cirrhosis complicated with intestinal obstruction patients and analyze its influencing factors, and provide basis for clinical intervention.@*Methods@#In Affiliated People′s Hospital of Hubei University of Medicine, a retrospective collection of 39 patients with decompensated cirrhosis complicated with intestinal obstruction from August 2018 to August 2019 were included in the observation group, including 25 males and 14 females, aged (52.34±2.64) years old, ranging from 39 to 64 years old. A total of 42 patients with decompensated cirrhosis not complicated with intestinal obstruction were selected as the control group by random number table method in simple random sampling, including 30 males and 12 females, aged (51.34±3.45), ranging from 37 to 68 years old. The patients in the two groups were investigated by using the chronic liver disease patient quality of life scale- chronic liver disease questionnaire. The abdominal symptoms, fatigue, systemic symptoms, activity, emotion, anxiety, and the total score of quality of life of the patients in the two groups were compared, and the influencing factors were analyzed. Among them, measurement data of normal distribution were expressed as (Mean±SD), and comparison between groups was evaluated by t test; Comparison of count data was evaluated by chi- square test. Factors affecting quality of life were analyzed by multiple linear regression.@*Results@#The scores of abdominal symptoms, fatigue, systemic symptoms, activity, emotion, anxiety and the total score of the observation group were (5.58±1.79), (4.23±1.74), (4.93±1.39), (5.36±1.36), (4.74±1.05), (4.26±1.25), (31.06±6.53), respectively. The scores of the control group were(6.27±1.12), (5.47±1.26), (6.14±0.78), (5.88±0.93), (5.45±0.82), (4.96±0.94), (33.79±4.01), respectively. The difference between the two groups was statistically significant (P< 0.05). Multiple linear regression results showed that disease course, child-pugh classification of liver function, discomfort symptoms such as abdominal pain, abdominal distension and fatigue, nutrition status, gender, age, medical expenses payment method, family per capita monthly income and anxiety were influencing factors.@*Conclusions@#Decompensated cirrhosis complicated with intestinal obstruction patients life quality is lower than decompensated cirrhosis not complicated with intestinal obstruction patients, and the influencing factors include disease-related factors and non-disease-related factors. Medical staff should give patients corresponding intervention according to their conditions to improve the quality of life of patients as much as possible.
RÉSUMÉ
Objective To explore the life quality of decompensated cirrhosis complicated with intestinal obstruction patients and analyze its influencing factors,and provide basis for clinical intervention.Methods In Affiliated People's Hospital of Hubei University of Medicine,a retrospective collection of 39 patients with decompensated cirrhosis complicated with intestinal obstruction from August 2018 to August 2019 were included in the observation group,including 25 males and 14 females,aged (52.34 ±2.64) years old,ranging from 39 to 64 years old.A total of 42 patients with decompensated cirrhosis not complicated with intestinal obstruction were selected as the control group by random number table method in simple random sampling,including 30 males and 12 females,aged (51.34 ± 3.45),ranging from 37 to 68 years old.The patients in the two groups were investigated by using the chronic liver disease patient quality of life scale-chronic liver disease questionnaire.The abdominal symptoms,fatigue,systemic symptoms,activity,emotion,anxiety,and the total score of quality of life of the patients in the two groups were compared,and the influencing factors were analyzed.Among them,measurement data of normal distribution were expressed as (Mean ± SD),and comparison between groups was evaluated by t test;Comparison of count data was evaluated by chi-square test.Factors affecting quality of life were analyzed by multiple linear regression.Results The scores of abdominal symptoms,fatigue,systemic symptoms,activity,emotion,anxiety and the total score of the observation group were (5.58 ± 1.79),(4.23 ± 1.74),(4.93 ± 1.39),(5.36 ± 1.36),(4.74 ± 1.05),(4.26 ± 1.25),(31.06 ± 6.53),respectively.The scores of the control group were(6.27 ± 1.12),(5.47 ± 1.26),(6.14 ± 0.78),(5.88 ± 0.93),(5.45 ± 0.82),(4.96 ± 0.94),(33.79 ± 4.01),respectively.The difference between the two groups was statistically significant (P ＜ 0.05).Multiple linear regression results showed that disease course,child-pugh classification of liver function,discomfort symptoms such as abdominal pain,abdominal distension and fatigue,nutrition status,gender,age,medical expenses payment method,family per capita monthly income and anxiety were influencing factors.Conclusions Decompensated cirrhosis complicated with intestinal obstruction patients life quality is lower than decompensated cirrhosis not complicated with intestinal obstruction patients,and the influencing factors include disease-related factors and non-disease-related factors.Medical staff should give patients corresponding intervention according to their conditions to improve the quality of life of patients as much as possible.
RÉSUMÉ
Traditionally,splenectomy is the second-line treatment method of primary thrombocytopenic purpura and a choice after the ineffectual treatment of glucocorticoid,but doctors never evaluate the curative effect of splenectomy before the operation and assess the necessity of splenectomy.In light of recent progresses on this topic,the current review summaries and pinpoints traditional application of splenectomy,side effects,new drug,and predicted factors of evaluation of operation,aiming to make accurate splenectomy for idiopathic thrombocytopenic purpura.
RÉSUMÉ
Splenectomy for patients with cirrhosis has been well established.However,many issues in relation to postoperative management of these patients remain to be elucidated,mainly including reasons for portal vein thrombosis and anticoagulant use.In light of recent progresses on this topic,the current review summaries and pinpoints influencing factors of portal vein thrombosis,anticoagulant selection and corresponding rationales,monitor measures for anticoagulation,and treatment schemes for bleeding induced by anticoagulation.Our review focuses on issues associated with the selection and withdrawal time of anticoagulant.We conclude that patients undergoing splenectomy can benefit from postoperative anticoagulation,including enhanced postoperative recovery and decreasing incidence of postoperative complications.