Résumé
Potassium is the major intracellular cation with concentrations reaching 120-150 mEq/L. On the contrary, the extracellular fluid potassium concentration is much lower and kept within very narrow levels between 3.5- 5.0mEq/L [1]
Aim of the work: this work aimed to assess serum potassium level in patients on regular hemodialysis and to determine its clinical impact on hemodynamic stability during the hemodialysis session
Patient and method: serum [K] level of 30 patients on regular hemodialysis was measured before and after dialysis and the results were correlated with electrocardiographic [ECG] changes
Results: there was no change in P wave, PR interval or QT interval in all the patients, while QRS was found to be shortened in 3 patients [10%] in the post-dialysis ECG and elongated in one patient [3.3%] in the post dialysis ECG, T wave showed dynamic changes in the form of reduction in the amplitude of T wave in 11 patients [36.7%]
Conclusion: the absence of electrocardiographic changes in hyperkalaemic haemodialysis patients should be interpreted with caution
Résumé
Background: Bone profile parameters are affected by decreased estimated GFR within chronic kidney disease stage 3. We aimed to investigate if bone profile parameters response to vitamin D3 supplementation , within this stage , became affected by the presence or absence of diabetic state
Materials and methods: 30 patients having chronic kidney disease [stage 3] were enrolled in the study. 19 patients constituted non - diabetic group I and 11 patients constituted diabetic group II . All of them have received vitamin D3 1000 IU daily for 3 months . For all patients the following measurements were performed before and after vitamin D3 use :CBC , ESR1 and ESR2 , blood urea , serum creatinine , estimated GFR , complete urine analysis , serum Na , protein / creatinine ratio , serum calcium , serum phosphorus , calcium - phosphorus product , serum albumin , serum alkaline phosphatase , and intact serum parathyroid hormone
Results: Serum calcium levels have increased, while intact parathyroid hormone has decreased within both groups , with a more obvious response within the diabetic group . Serum alkaline phosphatase , serum phosphorus , and calcium - phosphorus product did not show any significant change, they were within their level after vitamin d3 use .ESR 1 and ESR 2 levels were higher from the start of the study within the diabetic group. Their mean level values have significantly decreased in a highly significant way within this group . Kidney function parameters and proteinuria have been deteriorated within the two groups , being worse within the diabetic group
Conclusion: Vitamin D3 use within stage 3 chronic renal disease patients is effective for patients support against bone mineral disturbances occurring within this disease