1.
Journal of International Pharmaceutical Research
; (6): 1049-1053, 2016.
Article
de Chinois
| WPRIM
| ID: wpr-509091
RÉSUMÉ
Human protein tyrosine phosphataseβ(HPTPβ)is an endothelial cell-specific receptor protein tyrosine phospha?tase(PTP). HPTPβplays an important role in regulating pathophysiological processes such as angiogenesis and cell-to-cell adherens junction,and is taken as a novel target for developing new antiatherosclerosis and antitumor drugs. In this review,the latest research progress in the structure,physiological functions and small molecular inhibitors of HPTPβis summarized.