Prevalence of Migraine among patients of Depressive Disorder

Objective: To find out the prevalence of Migraine among patients of Depressive Disorder

Methods: A descriptive cross sectional study, conducted at Department of Psychiatry and Behavioral Sciences, JPMC, Karachi from 1st January 2014 to 30th June 2014. Total 272 patients were enrolled in the study. Depressive disorder was diagnosed as per ICD-10 criteria and Migraine headache as ICHD-2 criteria for diagnosis

Results: A total of 272 patients with mean age of 31.85 +/- 8.7 were enrolled. Out of 272 cases 64% were females; Out of total cases 86.4% were married. Migraine with aura was seen among 6.6% and migraine without aura was present among 26.1%. Migraine was linked more with females and married and of those having severe Depressive disorder

Conclusion: Migraine headache is common among depressed people, particularly females and having severe depression, so it ought to be remembered that while looking for Depressive disorder or headache the other condition must be remembered

Physical Co-morbidity according to ICD-10 criteria among patients with depressive disorder

Objective: To detect the prevalence of physical co-morbidities according to International Classification of Diseases[ICD-10] among patients with Depressive disorder

Design: Descriptive cross sectional study

Setting: Psychiatric consultation clinic of JPMC Karachi

Methods: Patients of either gender and age >18 years were consecutively selected after informed consent, Ethical issues were addressed according to Institutional Review Board [IRB], JPMC, Karachi. Patients with psychotic symptoms, personality disorders, dementia, and history of substance use were excluded. ICD-10 criteria, beside complete history, physical examination and lab investigations were used to confirm the diagnosis of depression and physical co-morbid. Prescribed questionnaire was used to collect the data and analyzed in SPSS version-17. Descriptive statistics were calculated for age, gender, marital status, education, socioeconomic status and co-morbidity

Results: Total 100 cases fulfilled the inclusion criteria. Their Mean +/-SD age was 32.7 +/-16.7 years. Both genders were equally vulnerable, [50% each]. Fifty three percent had moderate, 31% mild and 16% had severe depressive disorder. Hypertension was the most common [18%] in male patients and sinusitis was the most common [28%] in female patients with depression. Other co-morbidities included Diabetes Mellitus, Epilepsy, Migraine, HCV, Anemia, Chronic Kidney Disease [CKD], Urinary Tract Infection [UTI] and Menopausal syndrome [in women], Obesity, Asthma and Facial pain

Conclusion: Physical co-morbidities are prevalent among patients with depressive disorder. Presence of physical co-morbid may decreases the chances of treatment compliance, increases risk of treatment failure, relapse of depression, worse prognosis and elevated the treatment cost. Early detection and simultaneous management of these co-morbid with depression are suggested

Frequency of depression in patients undergoing coronary artery bypass grafting surgery [CABGS], before the surgery, at discharge and at six months follow up

Introduction: Depression is much frequent in patients undergoing CABGS. However, severity was reduced post operatively. Counseling and psychosocial interventions can play an important role in recovery and functionality of patients

Objective: To compare the frequency of depression in patients undergoing coronary artery bypass grafting surgery [CABGS] before the surgery, at discharge and at six months follow up

Design: Prospective, observational study conducted from Dec 2008 to Dec 2009

Setting: National Institute of Cardiovascular Diseases [NICVD] Karachi

Methods: One hundred and thirty four [134] patients of 18+ years old who were consecutively listed for first time CABGS were included in the study after fulfilling the inclusion and exclusion criteria and addressing the ethical issues. ICD-10 criteria to diagnose and Hamilton Rating Scale for Depression [HAM-D] were applied to assess the frequency and severity of depressive disorder respectively. Results were analyzed using SPSS version 17.0

Results: One hundred and thirty four [134] patients undergoing CABGS fulfilled the criteria for Depressive disorder. One hundred and thirteen [84.3%] were male and 21 [15.7%] were female with age range 33 to 75 years [mean 53.7 +/-SD 8.57]. Preoperatively 132 [98.5%] patients and postoperatively 108 [80.6%] patients were depressed. At 6 months follow up which was available in 73 patients, only 12 [16.4%] were found depressed. Both genders were almost equally affected. Surprisingly age, ethnicity, education and co-morbids did not show a significant role

Conclusion: Depression is commonly reported before and after cardiac surgery procedures and it significantly influences the quality of life of the patients undergoing CABGS. The consequences can increase morbidity and mortality