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An. bras. dermatol ; 95(3): 343-346, May-June 2020. graf
Article Dans Anglais | LILACS, ColecionaSUS | ID: biblio-1130895

Résumé

Abstract Cutaneous tuberculosis is a rare extrapulmonary manifestation of tuberculosis which, like disseminated tuberculosis, commonly occurs in immunocompromised patients. Poncet reactive arthritis is a seronegative arthritis affecting patients with extrapulmonary tuberculosis, which is uncommon even in endemic countries. We report a previously healthy 23-year-old male patient with watery diarrhea associated with erythematous ulcers on the lower limbs and oligoarthritis of the hands. Histopathological examination of the skin showed epithelioid granulomatous process with palisade granulomas and central caseous necrosis. AFB screening by Ziehl-Neelsen staining showed intact bacilli, the culture was positive for Mycobacterium tuberculosis, and colonoscopy revealed multiple shallow ulcers. Disseminated tuberculosis associated with reactive Poncet arthritis was diagnosed, with an improvement of the clinical and skin condition after appropriate treatment.


Sujets)
Humains , Mâle , Jeune adulte , Tuberculose cutanée/immunologie , Tuberculose cutanée/anatomopathologie , Sujet immunodéprimé , Arthrite réactionnelle/immunologie , Immunocompétence , Pyrazinamide/usage thérapeutique , Rifampicine/usage thérapeutique , Ulcère cutané/immunologie , Ulcère cutané/anatomopathologie , Ulcère cutané/traitement médicamenteux , Tuberculose cutanée/traitement médicamenteux , Résultat thérapeutique , Éthambutol/usage thérapeutique , Isoniazide/usage thérapeutique , Mycobacterium tuberculosis/isolement et purification , Antituberculeux/usage thérapeutique
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