Résumé
The purpose of this study was to compare the clinical efficacy of resin modified GIC with amalgam as a restorative material, in Class-II cavities of primary molars. Restorations were evaluated at four, eight, and twelve months for their marginal integrity, anatomic form and development of recurrent caries. When each parameter was considered separately, there was no difference in the success rate between the two groups, except development of recurrent caries significantly less (p<0.05) in RMGIC group(4.7%) compared to amalgam group (12.5%) at twelve month follow up. However, the cumulative success rate at 12 month was found to be significantly higher (p<0.05) in RMGIC (Fuji II LC) group(83.1%) compared to amalgam(72%).
Sujets)
Enfant , Enfant d'âge préscolaire , Alliage dentaire/composition chimique , Amalgame dentaire/composition chimique , Caries dentaires/étiologie , Restaurations dentaires permanentes/classification , Études de suivi , Ciment ionomère au verre/composition chimique , Humains , Adaptation marginale (odontologie) , Molaire/anatomopathologie , Récidive , Céments résine/composition chimique , Résines synthétiques/composition chimique , Argent/composition chimique , Propriétés de surface , Dent de lait/anatomopathologie , Résultat thérapeutiqueRésumé
Patients of idiopathic membranous nephropathy (MGN) were randomly assigned to received steroid and cyclophosphamide every other month (Gr-I) and steroid alone (Gr-II). Of 36 patients in Gr.I, 33 patients achieved complete remissions, 2 had relapsing course with remission on further courses of therapy and only one has reached end stage renal failure. In contrast, of the 35 patients in Gr. II, 15 (P < 0.001) achieved complete remission, 7 are in partial remission, 5 have no response, another 5 have deterioration of renal function of which two required dialysis, and 3 have relapsing course after the initial remission. Mean follow up period was 46 +/- 10.2 months. We conclude that steroid and cyclophosphamide every other month is highly effective in achieving remission in patients with membranous nephropathy.
Sujets)
Adolescent , Adulte , Sujet âgé , Cyclophosphamide/administration et posologie , Relation dose-effet des médicaments , Calendrier d'administration des médicaments , Association de médicaments , Femelle , Études de suivi , Glomérulonéphrite extra-membraneuse/traitement médicamenteux , Humains , Mâle , Adulte d'âge moyen , Prednisolone/administration et posologie , PronosticRésumé
In early infancy splenic white pulp is seen arranged around the central arterioles. They do not show any reactive changes even in the presence of systemic infections. Lymphoid follicles are seen at 6 weeks of life. Germinal centres appear from the 8th week of life onwards. Periarteriolar lymphocytic sheaths persist in the older children along with the reactive changes.