Immediate changes in pupil size following laser in situ keratomileusis [LASIK]: pupillometry study

To investigate the impact of laser in situ keratomileusis [LASIK] on the change in pupil size immediately after the procedure. In a prospective study, measurement of pupil size was assessed in 70 eyes of 35 consecutive patients using a hand-held pupillometer before and immediately after LASIK in mesopic condition at the refractive eye center, Riyadh, Saudi Arabia. The pupil showed mild dilation immediate after LASIK. Mean pupil size before LASIK was 4.10 +/- 0.74 and immediate after was 4.74 +/- 0.82, P value <0.0001. No association was found with age, sex, central corneal thickness or pre-operative refractive measurements [CCT]. There is a change in pupil size that immerses immediately after LASIK; postulations suggested for papillary dilation include the effect of suction ring, post-operative steroid eye drops, dark room, pain and anxiety

In vitro anthelmintic activity of Peganum harmala L. against Fasciola gigantica

In the present work, the seeds of the medicinal plant Peganum harmala L.were extracted by both water and methanol to evaluate their in vitro anthelmintic activity against fasciola gigantica. RPMI 1640 medium was used for maintenance of the parasite in culture. The highest concentrations of the seeds aqueous extract of Peganum harmala of 15000 and 5000 ppm gave 100% mortality one hour after the parasite exposure to the extract. The lower concentrations had revealed no effect against the parasite, except the concentration 1000 ppm which gave 25% mortality in the second hour and reached 100% mortality after the 6th. hour of exposure. The seed methanolic extract of Peganum harmala was significantly [P<0.001] potent and revealed mortality at both 1000 and 500 ppm as follows: 17, 17, 83, 100 and 100% and 0, 0, 17, 66, 83% respectively, at the exposure times of 1, 2, 3, 6 and 24 hours