Your browser doesn't support javascript.
loading
Montrer: 20 | 50 | 100
Résultats 1 - 1 de 1
Filtre
Ajouter des filtres








Gamme d'année
1.
Indian J Med Microbiol ; 2007 Jul; 25(3): 267-71
Article Dans Anglais | IMSEAR | ID: sea-53673

Résumé

There is only scanty data on the effects of specific antibody, with or without complement, on Candida albicans or Candida krusei in cell-free systems in vitro, although previously published work has shown that specific antibody mediates anti- Candida immunity in vivo by inhibition of adherence to host cells or surfaces and by the promotion of phagocytosis and intra-phagocytic killing. The MTT (3-[4, 5-dimethyl-2-thiazolyl] -2, 5-diphenyl -2H- tetrazolium bromide)-reduction method as a test of the viability of fungi was used to investigate the effect of complement, normal serum and immune serum on these two species of Candida that are of increasing importance as opportunistic pathogens. We report that normal rabbit serum or strain-specific, polyclonal anti- Candida rabbit antibody, with or without guinea pig complement, did not cause the reduction of total cell-mass or of the viability of either C. albicans or C. krusei, in vitro as determined by the MTT-reduction test. Complement alone without specific antibody, also, had no such effect on these two Candida species.


Sujets)
Animaux , Anticorps antifongiques/immunologie , Spécificité des anticorps , Candida/immunologie , Candida albicans/immunologie , Protéines du système du complément/immunologie , Cochons d'Inde , Sérums immuns/composition chimique , Oxydoréduction , Lapins , Spécificité d'espèce , Sels de tétrazolium/composition chimique , Thiazoles/composition chimique
SÉLECTION CITATIONS
Détails de la recherche