Deep sclerectomy versus trabeculectomy in management of primary open angle glaucoma

Aim of the work: This work aims to evaluate the efficacy of deep sclerectomy in management of primary open angle glaucoma, with its possible complications through a comparative study with the traditional filtering surgery trabeculectomy. Patient and methods: Thirty eyes of 28 glaucoma patients, whom were diagnosed as primary open angle glaucoma, were randomly divided into two groups each of 15 eyes, group I: Patients were subjected to trabeculectomy operation. Group II: Patients were subjected to deep sclerectomy operation. The two groups were followed postoperatively for detection of any complications Results and discussion: The deep sclerectomy as non penetrating glaucoma surgery lowers the intraocular pressure as good as the standard trabeculectomy. Its complication rate is very low during the early postoperative weeks

Effect of squalamine on iris neovascularization in monkeys

The purpose of this study was to investigate the effect of squalamine, an antiangiogenic aminosterol, in an experimental model of iris neovascularization. Iris neovascularization was created in cynomolgus monkeys by occluding retinal veins with an argon laser and inducing persistent hypotony with a central corneal suture. Twenty-four eyes were treated in three groups. In group 1, 4 eyes were injected intravitreally with 3 mug/0.1 ml squalamine and four eyes with balanced saline solution [controls] immediately after vein occlusion [day 1]; injections were repeated every three days for three weeks. In group 2, 1 mg/kg squalamine was administered with intravenous infusion in dextrose 5% in four animals; 4 control animals received only dextrose. Infusions began on day 1 and were repeated every 3 days for 3 weeks. In group 3, after the development of iris neovascularization on day 7, 1 mg/kg squalamine was injected systematically in 4 animals; 4 animals received dextrose 5%. Monkeys were examined by slit-lamp biomicroscopy and underwent color photography and fluorescein angiography. The study concluded that intravitreally injected squalamine did not affect the development of iris revascularization; however, systemic squalamine injection inhibited the development of iris revascularization and caused a partial regression of new vessels in a primate model

Modified new technique of dacryocystorhinostomy [DCR]

The results of new fashioned technique of D C R for treatment of chronic dacryocystitis in adults, using motorised dental bur were reviewed. The planning for surgical intervension had been decided after failed repeated probing. Relief of epiphora and discharge was achieved in 90% of patients underwent initial D.C.R. This method of dacryocystorhinostomy with insertion of urologic catheter in the osteotomy window was effective, less time consuming secondary procedure in whom probing was unsuccessful

Study of the incidence of giant papillary conjunctivitis with different contact lenses

This study was done to document the effect of SCL on the Egyptian patients conjunctiva. One hundred patients had been followed up during the previous 2 years. The adverse conjunctival reaction known by GPC were seen in 24 cases in this study all, the wearers were used soft lens and non of the hard wearers showed this syndrome. Also extended wear SCL wearer were more prone to the development of this adverse reaction than the daily wear lenses by 4:1