[Personality, intellectual and emotional state of patients with borderline personality disorder]

It is possible to explain the great discrepancy in the personality and psychopathology of patients with borderline personality disorder [BPD], partly, on the basis of differences in their profiles of personality, psychopathology, intellectual and emotional state. The aim of the current study was to assess these items in the patients with BPD. This was a descriptive-comparative study. Among the patients with diagnosis of BPD referring to Sanandaj health centers, 30 accepted to participate in this study. They were assessed by use of MCMI-III, emotional state questionnaire, and The WAIS-R. The results were compared with those of their matched, non-clinical group. SPSS software was used for data processing and data were analyzed by profile analysis and one way ANOVA. Profile analysis showed significant differences between the groups in all of the tests. Comparison of the single scales showed differences in a wide range of variables of personality, intellectual and emotional state. The results indicated an important role for the emotional elements in the development of personality disorders and also similarity of many of the clinical symptoms in these patients. Intellectual elements are also useful for explaining a fundamental part of the symptoms of BPD. These variables seem essential for understanding cognitive, affective and behavioral aspects of the patients with BPD

[Evaluating the effects of pentoxifylline administration on experimental pressure sore in rats by biomechanical examinations]

The aim of the present investigation was to study the effect of pentoxifylline administration on wound healing process of an experimental pressure sore in rat by biomechanical evaluating method. In ten adult male rats under general anesthesia and sterile conditions one experimental pressure sore by no20Halsted mosquito forceps were made. A double layer folded skin of dorsal region were held under most pressure grade of the forceps for 2 hours. It was followed by 30 minutes[the skin] relaxation. This procedure was repeated for 12 times during three consecutive days. Seven days later pressure sore was made. Rats were divided into control and experimental groups. Pentoxifylline was injected intraperitonealy at a dose of 50mg/kg daily from beginning of pressure sore for twenty days. After these procedures rats were killed by chloroform, and samples were extracted from the wound and surrounding skin. Samples were biomechamcally examined by a material testing instrument and maximum stress [N/mm[2]] work up to maximum force [Nmm]. The young modulus of elasticity [N/mm] were them calculated. In experimental group maximum stress [2.05 +/- 0.15] and work up to maximum force [63.75 +/- 4.97] were significantly higher than those of control group[1.3 +/- 0.27] and[43.3 +/- 14.96] [p-0.002 and p=0.035 relatively]. Pentoxifylline administration in rats which had an experimental pressure sore significantly accelerated wound healing process compared to those of control group which was observed by biomechanical examination