Polycystic ovarian disease a study of 14 cases

Fourteen cases of polycystic ovarian disease were diagnosed. The diagnosis was based on clinical presentation, laboratory data, and histological picture for the nine patients who had an ovarian wedge resection. The results of the treatment of these cases were discussed comparing the return of menstruation, ovulation and pregnancy rate between the group treated with clomiphene citrate and the group who failed to respond to clomiphene and were managed by ovarian wedge resection. The conclusive results of our series at both the diagnostic and therapeutic level were in agreement with findings of various authors. At the diagnostic level we found that although the diagnosis of polycystic ovarian disease is a clinical one, the elevated serum LH and testosterone [plasma] will support the diagnosis. The therapeutic value of clomiphene citrate is rather limited but we still believe that those cases diagnosed clinically as polycystic ovarian disease should not be subjected to invasive procedure before they were given at least six months course of clomiphene supplemented by LH. The medical literature and opinions of various authors are discussed regarding diagnosis, treatment and pathogenesis of polycystic ovarian disease

Ectopic pregnancy at Riyadh Maternity Hospital: a study of 45 cases

Forty-five cases of ectopic pregnancy were reported with an incidence of 1:742 pregnancies. Approximately forty percent [40%] of these patients gave positive past history of infertility, pelvic infection or abdominal operation. Eighty-five percent [85%] cases were among gravida 1-5 but nulliparous and grandmultipara were in the low risk group. In 88% of the cases, it was tubal ectopic, with 58.5% in the right fallopian tube. History of amenorrhea and low abdominal pain with tenderness were the presenting features in 95% of cases while vaginal bleeding was reported by 50%. Vaginal examination is singled out as of poor diagnostic value but laparoscopy was the best diagnostic procedure. The medical literature was reviewed in its relevance to the incidence, clinical presentation and aetiology