Résumé
A facile method has been implemented for the synthesis of different N-substituted sulfamoylacetamides by reacting 4-acetamidobenzenesulfonyl chloride [1] with different alkyl/aralkyl/aryl amines [2a-q] in basic aqueous media under controlled pH to afford -[[Substitutedsulfamoyl] phenyl]acetamides [3a-q] which were confirmed through spectral analysis like FT-IR, EIMS and [1]H-NMR. Moreover, the synthesized derivatives were screened against alpha-Chymotrypsin. The enzyme inhibitory results revealed that most of the synthesized compounds were found to be moderate enzyme inhibitors
Résumé
A total of 184 patients were examined for their blood uric acid level. Sixty two [33.69%] were found to be hyperuricemic while none was found to be hypouricemic. Analysis of the results indicated a higher risk of hyperuricemia in patients, in age group of 30 and above especially females and those with O blood group. The prevalence of hyperuricemia was also higher in patients using a protein-rich diet, being poor with respect to their socio-economic position and those suffering from gout, rheumatic fever or liver and kidney diseases
Sujets)
Humains , Mâle , Femelle , Acide urique/analyse , Maladies du rein/diagnostic , Goutte/diagnosticRésumé
Acacia nilotica seeds have been tested for their germination performance at 37°C and at room temperature before and after priming treatments at 20°C using either pure distilled water or solution of PEG-6000, CaCO[3], and NaCl for 20 days. Untreated controls showed weak germination profiles while priming in water proved to be the most effective in increasing the germination performance of these seeds. However, even this treatment could not increase the germination percentage of these seeds beyond 12.5%. We, therfore, conclude that although priming affects the total number of seeds germinated and spread of germination of Acacia nilotica seeds, it alone is unable to generate any dramatic change in the germination performance of these seeds