Résumé
Objective: To evaluate the success of systemic single-dose methotrexate [MTX] treatment in patients with ectopic pregnancy [EP] and to investigate factors related to treatment success
Methods: This retrospective study had been performed in Yildirim Beyazit University between January 2010 and December 2015. Demographic and clinical characteristics, ultrasonografic findings, pretreatment serum beta-human chorionic gonadotropin [beta-hCG] and progesterone levels of 58 patients with EP were retrieved from hospital records retrospectively. The patients were grouped according to MTX treatment success [response vs. failure]
Results: Single-dose MTX-treatment was successful in 72.4% [42/58] of patients. The mean pretreatment beta-hCG level was significantly lower in responders than in failures [2080 +/- 2322 vs. 5707 +/- 3885 IU/L, p = 0.001], and 2678 IU/L was the most suitable cutoff to predict success [75% sensitivity, 73.8% specificity]. Moreover, failure rate was 8.45 times more in group of patients whose beta-hCG values were determined above the cutoff. The presence of fetal cardiac activity adversely affected treatment success [odds ratio = 12, p = 0.004]. Treatment success was not affected by past history of ectopic pregnancy, thickness of endometrium, progesterone value or presences of pseudosac and free pelvic fluid
Conclusion: The success rate of single dose MTX in this study was 72.8 %, and we found that failure rate of MTX treatment was 8.45 times more in group of patients whose initial serum beta-hCG values were above 2678 IU/L and 12 times more in patients with fetal cardiac activity
Résumé
The aim of this study was to determine the incidence of Post Partum Thyroiditis [PPT] at first month postpartum. Fifty pregnant subjects were included. Control group was composed of 50 women who did not give birth in the recent year. Blood samples were obtained once in the control group and twice -at the third trimester and the first month postpartum-in the pregnant group. PPT occurred at first month postpartum in 3 of 50 pregnant women. The incidence of PPT at first month postpartum was 6%. Among the pregnant group, there was a statistically significant increase in the Anti-TPO and Anti-Tg levels within the first month postpartum compared to the ones in the third trimester. Also, all patients who experienced PPT were positive for Anti-TPO and Anti-Tg. In our opinion, it will be useful to evaluate particularly the pregnants with positive thyroid auto-antibodies in early postpartum period
Résumé
To determine the effects of Ramadan fasting on dietary intakes, nutritional status and biochemical parameters of Turkish pregnant women. We carried out this study at Dr. Zekai Tahir Burak Women's Health Care and Research Hospital, Ankara, Turkey from October 15th to November 13th 2004. Forty-nine fasting group and 49 non-fasting group [control group] voluntarily enrolled for the study. We analyzed the blood biochemical parameters of pregnant women and obtained the dietary intakes from the groups. Compared to the control group, weight gain and energy intake [p<0.05 for second and third trimesters] was less in the fasting group. The percentage of protein [p<0.05 for first and second trimesters] and carbohydrates [p<0.05 for all trimesters] from total energy was higher in the fasting group than in the control group. We noticed a slight increase in the fasting blood glucose, serum total cholesterol high-density lipoprotein-cholesterol and triglycerides [p<0.05 for first trimester] concentrations in the fasting group during Ramadan. However, we found decreased levels in the plasma urea, total cholesterol, triglycerides, low-density lipoprotein-cholesterol and total protein and albumin levels of the fasting group in comparison with the control group. Dietary mineral and vitamin intakes were lower than the recommended daily allowance, except vitamin A and vitamin C in both groups. Based on the results of the present study, Ramadan fasting had no significant adverse effect on the health of pregnant women