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2.
Biol. Res ; 47: 1-5, 2014. ilus, tab
Article Dans Anglais | LILACS | ID: biblio-950739

Résumé

BACKGROUND: Pure mucinous adenocarcinoma of the breast is a rare entity characterized by the production of variable amounts of mucin comprising 1% to 6% of breast carcinomas. Some mucinous adenocarcinomas have shown expression of intestinal differentiation markers such as MUC-2. This study examines the expression of intestinal differentiation markers in this type of breast carcinoma. RESULTS: Twenty-two cases of pure mucinous adenocarcinoma of the breast were assessed. Immunochemistry was performed for beta-catenin, CDX-2 and MUC-2. All cases were positive for B-catenin. MUC-2 positivity was observed in all cases; 63. 6% were 3 plus positive. All cases were negative for CDX-2. CONCLUSIONS: These results suggest that mucinous breast carcinomas express some markers of intestinal differentiation, such as MUC-2 and beta-catenin; however, future studies with a larger series of cases and using molecular techniques that help affirm these results are needed.


Sujets)
Humains , Femelle , Adulte , Adulte d'âge moyen , Sujet âgé , Sujet âgé de 80 ans ou plus , Tumeurs du sein/composition chimique , Marqueurs biologiques tumoraux/analyse , Transactivateurs , Adénocarcinome mucineux/composition chimique , Protéines à homéodomaine/analyse , bêta-Caténine/analyse , Mucine-2/analyse , Muqueuse intestinale/composition chimique , Tumeurs du sein/anatomopathologie , Immunohistochimie , Antigènes de différenciation/analyse , Études rétrospectives , Adénocarcinome mucineux/anatomopathologie , Facteurs de transcription CDX2
3.
Bol. Col. Mex. Urol ; 13(3): 147-9, sept.-dic. 1996. ilus
Article Dans Espagnol | LILACS | ID: lil-187774

Résumé

Los carcinosarcomas renales son tumores bifásicos raros (1.5 por ciento) compuestos por áreas epitelioides y fusocelulares sarcomatosas. El diagnóstico diferencial incluye lesiones primarias y metastásicas en el riñón. En este artículo se informan los hallazgos histopatológicos de inmunohistoquímica y ultraestructura, así como los criterios de diagnóstico descritos en la bibliografía


Sujets)
Humains , Mâle , Sujet âgé , Carcinosarcome/diagnostic , Carcinosarcome/anatomopathologie , Immunohistochimie , Tumeurs du rein/diagnostic , Tumeurs du rein/anatomopathologie
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