1.
Rev. bras. hematol. hemoter
;
34(5): 367-382, 2012. tab
Article
Dans Anglais
| LILACS
| ID: lil-654979
2.
Rev. bras. hematol. hemoter
;
33(2): 131-139, 2011. ilus, tab
Article
Dans Anglais
| LILACS
| ID: lil-596303
Résumé
Dasatinib is a highly effective second generation tyrosine kinase inhibitor approved for the treatment of imatinib-resistant or intolerant chronic myeloid leukemia and Philadelphia-positive acute lymphoblastic leukemia. This article reviews the results of phase I, II and III studies and looks at the efficacy and safety of dasatinib. This review also provides practical recommendations for the management of side effects.