Effect of aerobic exercise along with core muscle strengthening in young individuals with constipation: randomized controlled trial

Background: Constipation is traditionally defined as infrequent bowel movements or hard faeces. Patients report a variety of symptoms, including decreased bowel motion frequency, straining, hard stools, the sensation of incomplete emptying, the sensation of anal blockage, or the use of digitation or positioning to aid defecation. Physical health, mental health, and social functioning are all compromised in affected individuals. Despite this, only one-fifth of constipated people seek medical attention. Constipation symptoms are reported by 10% to 20% of adults worldwide. This study investigated the effects of aerobic exercise along with core muscle strengthening on young individuals with constipation. Methods: The study included 50 participants having constipation. The participants were randomly allocated in two groups. The intervention period was of 4 weeks. The exercises were explained to all individuals and pre and post treatment PAC SYM (patient assessment of constipation symptoms) and PAC-QOL (patient assessment of constipation quality of life) questionnaire scoring along with Rome IV criteria was taken. Results: In group A, post-treatment values of PAC SYM and PAC QOL were significantly lower than pre-treatment values. The post-treatment comparison of two groups revealed a significant difference in PAC SYM and PAC QOL, with group B showing a significant reduction in PAC SYM and PAC QOL compared to group A. Conclusions: The present study concluded that individuals who underwent both aerobic and core strengthening training showed more improvement than individuals who performed aerobic training alone.

Coverage Of Multiple Maxillary Gingival Recessions Using Coronally Advanced Flap With Subepithelial Connective Tissue Graft: A Case Report

Background:This case report describes treatment of multiple gingival recession with subgingival connective tissue graft and coronally advanced flap technique in treatment of maxillary teeth. Material And Methods:Connective tissue grafting wasdone in relation to upper right second premolar, first premolar, canine, right central incisor, left central incisor and left lateral incisor (#15,#14,#13,#11,#21,#22). A split thickness flap was elevated without disturbing periosteum in this region. The area between canine and second premolar was selected to harvest the graft. The graft was placed on the recipient bed and suturing was done. Result:Predictable root surface coverage could be obtained with use of coronally advanced flap and subepithelial connective tissue graft. Conclusion:Subepithelial connective tissue graft along with coronally advanced flap still stand as a gold standard treatment for gingival recession coverage.

Treatment Of Bilateral Gingival Recession Using Coronally Advanced Flap And Amniotic Membrane On One Side And Coronally Advanced Flap And PRF Membrane On Other Side: A Case Report

Gingival Recession is a common, complex, and unpleasant clinical condition. It is more commonly associated with root hypersensitivity, impaired esthetics and root caries. Successful treatment outcome becomes challenging in such cases. Coronally advanced flap for rootcoverage is most commonly used technique. Combination of biological membranes derived from human body itself along with coronally advanced flap yields better results. This case report describe s a case of bilateral Class I gingival recession treated with amniotic membrane on one sideand PRF membrane along with Coronally advanced flap on other side.

Smartphone addiction among undergraduate medical students and its association with academic performance

Background and aims: Smartphones have become an indelible part of a student’s life; but, their effect on academic performance of medical students is unclear with sparse data. The objective of the study was to estimate the prevalence of smartphone addiction among undergraduate medical students, pattern of its use, and the association of smartphone addiction with academic performance. Method: We conducted a cross-sectional study on all the undergraduate medical students in the Medical College Baroda, Anandpura, Vadodara, Gujarat, India, from second year to internship after getting written informed consent. Sociodemographic details, patterns of smartphone use, and scores of the final examination appeared for, were obtained to assess academic performance using a self-report semi-structured questionnaire. Smartphone addiction was diagnosed using the Smartphone Addiction Inventory (SPAI). Result: Out of the 523 students approached, 427 returned completed questionnaires. Ninety five students (22.2%) had smartphone addiction, with the addicted students being more likely to change their phone often, use it for longer periods and in restricted places. No association was found with gender, age, years of use, and academic performance. Conclusion: Nearly one-fifth of the medical undergraduate students were suffering from smartphone addiction. However, it does not seem to have an association with academic performance among undergraduate medical students.

Depression--an adverse event with nifedipine.

Two cases are reported in which depression was associated with the use of calcium channel blocker, nifedipine. In one instance, a patient became unresponsive to treatment with nortriptyline when nifedipine was introduced. In both cases, the depression resolved following discontinuation of nifedipine.

Regeneration from leaf protoplasts of Arabidopsis thaliana ecotype estland.

Protoplasts (2 x 10(7)/g fresh wt) were isolated from leaves of A. thaliana ecotype estland, with a viability of more than 90%. Protoplasts cultured in calcium alginate beads or layers showed division while culture in liquid or agarose beads failed to elicit any division. Effect of culture density showed highest frequency of division occurring at 5 x 10(5) while no division was seen when cultured at a density of 5 x 10(4). Culture in MS medium resulted in higher division frequency and better sustenance of microcolonies as compared to B5 medium. Under optimized conditions, macrocolonies were formed at a frequency of 1.8%. Shoot regeneration was seen in 50% of microcalli transferred to shoot induction medium for regeneration. Shoots were rooted and plantlets transferred to pots. The plants produced flowers and were fertile.

Spontaneous expulsion of unusual tracheobronchial foreign body.

An extremely rare case of long, thin and sharp pin in a young boy which was inhaled initially and defied removal at branchoscopy was eventually recovered in stool after a long and variable course through alimentary tract has been reported.

Oxidant-antioxidant status in acute and chronic renal failure.

Present study was carried out to evaluate oxidant-antioxidant status and effect of hemodialysis in acute and chronic renal failure. Serum MDA levels increased while serum SOD found decreased significantly. This study indicates the existence and increased production of an oxidizing stress resulting from hemodialysis and disturbance in antioxidant enzyme system.

Multidrug resistant Salmonella.

A total of 326 salmonella strains was isolated and studied from suspected enteric fever cases in Mumbai (Bombay) during a 2 year period from May 1992 to July 1994. These were identified using standard biochemical and serological tests. Bacteriophage typing, antibiotic sensitivity and conjugation experiments were also carried out. S. typhi was the most common serotype accounting for 75.46% of the strains. Among S. typhi strains 87% were biotype I and 13% were biotype II. 9.5% strains were of S. paratyphi A, 5.52% of S. typhimurium, 4.60% of S. worthington, 4.30% of S. havana and 0.62% of S. enteritidis. The commonest bacteriophage type of S. typhi was E1, and of S. paratyphi A type 1, whereas 88.88% strains of S. typhimurium were untypable. Most of the strains were multidrug resistant including commonly used antibiotics such as chloramphemicol, ampicillin, and cotrimaxazole. Quinolone derivatives such as Ciprofloxacin were found to be the most effective drugs. In the conjugation experiments there was direct transfer of resistance pattern and enbloc transfer of resistance was observed in most strains. Salmonella typhi is still the most commonly encountered species. There is an alarming increase in multidrug resistance.

Exudative v/s transudative ascites: differentiation based on fluid echogenicity on high resolution sonography.

Real time sonography was performed in 52 patients with ascites to evaluate the accuracy of sonography in differentiating an exudative from a transudative collection. The echogenicity of ascites was graded I, II and III using the echogenicity of normal abdominal viscera as comparative standard reference points. Grade I collections (31 patients) were either absolutely anechoic, or showed few internal echoes secondary to particulate matter. Grade II collections (7 patients) were hypoechoic as compared to the liver and spleen. Grade III collections (14 patients) had an echogenicity similar to or greater than that of the liver and spleen. The results of diagnostic aspiration in all patients were then compared to the sonographic grade of the ascitic fluid. All transudates (28 patients) had a Grade I echogenicity. Only 3 patients with an exudative ascites had a Grade I echogenicity. The remaining 21 patients with an exudative collection had an echogenicity equal to or greater than Grade II. Using these results, an ascitic fluid echogenicity of Grade I had a 92.32% sensitivity, 100% specificity, a positive predictive value of 1 and a negative predictive value of 0.875 in diagnosing transudates. An ascitic fluid echogenicity of Grade II or more had a sensitivity of 87.5%, specificity of 100%, a positive predictive value of 1 and a negative predictive value of 0.903 in diagnosing transudates.

Oral versus axillary temperatures in human volunteers.

We measured the oral and axillary temperatures of 100 individuals (including 40 females) in the medical wards. Twenty six had fever ranging from 37.3 degrees C to 40.5 degrees C while the rest had normal temperature. Although the oral temperature was higher than axillary temperature in all the cases, there was no correlation between the two; in one case the difference was as high as 1 degrees C. We conclude that while recording temperature the site must be clearly stated, and no attempt must be made to extrapolate the axillary to the oral temperature.