Résumé
Objective To learn the HIV infection status and related factors among spouses of HIV/AIDS. Methods We recruited HIV/AIDS cases diagnosed between January 2000 and August 2016 in Lu'an and their spouses to collect the demographic information and sexual behavior characteristics. For HIV sero-accordant spouses, we analyzed influencing factors for HIV infection by logistic regression model; while for HIV sero-discordant spouses, we followed up until December 31, 2016 and detected their HIV antibody periodically. Results The HIV infection rate of spouses was 20.35% (47/231) . Forty-five of the spouses had been infected with HIV before our investigation, with a infection rate of 19.48% (45/231) . Two of the spouses developed positive HIV antibody during the follow-up with a positive conversion rate of 0.39/100 person-years. Multivariate logistic regression analysis indicated that high frequency of sexual contacts before confirmed as HIV positive (OR≥1/week= 6.268, 95%CI:2.313-16.985; OR1/half a month=3.760, 95% CI: 1.268-11.150) and diagnosis during 2011-2014 (OR=3.079, 95% CI:1.209-7.841) were the risk factors for HIV transmission between couples; under the age of 25 (OR=0.042, 95% CI:0.004-0.467) when confirmed as HIV positive and early viral load＜300 copies/mL (OR=0.115, 95%CI: 0.045-0.295) were protective factors. Conclusion HIV transmission of spouses is associated with frequency of sexual contacts, time of diagnosis, age when confirmed as HIV positive and early viral load.