Advances on the impact of targeted temperature management on sepsis / 中国小儿急救医学

Targeted temperature management mainly affects the progression of sepsis by inhibiting inflammatory response, protecting mitochondrial function and reducing metabolism, which can improve survival, the prognosis and outcome of sepsis to some extent.Targeted temperature management has a positive impact on the occurrence and development of sepsis, which may be an adjuvant treatment method of sepsis.This review summarized the mechanism studies on the impact of targeted temperature management on sepsis in recent years, and summarized the existing problems, so as to provide reference for carrying out practical research on targeted temperature management for patients with sepsis.

Advances on the assessment of sedation in pediatric intensive care unit / 中国小儿急救医学

Sedation therapy is an important part of the safety and comfort management of critically ill children.The accurate selection of a sedation assessment tool can help nurses effectively assess the level of sedation and guide clinical care.This review summarized the existing six commonly used sedation assessment scales in pediatric intensive care unit, such as the Ramsay Sedation Scale, Richmond Agitation-Sedation Scale and Comfort Scale and related sedation concepts.Our study aims to provide a reference for choosing a sedation assessment scale suitable for critically ill children and standardizing sedation nursing practice.