Patterns of Lesions in Hysterectomy Specimens: A Prospective Study.

Hysterectomy is the most commonly performed gynaecological surgery throughout the world. Few studies have been performed describing the pathologic findings in hysterectomy specimens and examining the relationship between the preoperative clinical indication and pathologic diagnosis. This study was undertaken to identify the most common pathologies in hysterectomy specimens and to correlate the findings with the clinical indications. Six hundred and ninety eight cases studied over a period of one year formed the subject of the present study. Surgical specimens were formalin fixed and tissue was adequately processed from them. The sections were stained routinely with hematoxylin and eosin stain. Menorrhagia, fibroid uterus and uterovaginal prolapse were the most common clinical indications for hysterectomy. The most common pathologies identified were atrophic endometrium in endometrium, leiomyoma in myometrium, chronic cervicitis in cervix, ovarian cysts in ovaries and salpingitis in fallopian tubes. The pathologic examination confirmed the clinical diagnosis in majority of the cases.

Study Into The Patterns of Male Genital Tract Tumors.

Pattern of a particular disease in any population is studied with the idea of getting information about the clinical presentation, the varied morphology and the aetiological factors that can be assessed in relation to the prognosis. Our study was undertaken with the view to getting information about the prevalence , clinical presentation and morphological patterns of the tumors of the male genital tract..A total number of 111 histological proven cases of male genital tumors diagnosed over a period of 11 years were studied. The overall prevalence rate of male genital tumors was 0.94/1000 surgical admissions for histologically proven cases. The peak prevalence of male genital tumors was seen in the age group of 51-60 years.Penile cancers were the most commonly encountered malignancies accounting for 39.63% followed by prostatic adenocarcinomas 35.13%. Third in frequency were testicular tumors 34.32%. A single case (0.9%) of adenomatoid tumor of epididymis was seen.

Congenital Leukemia.

Congenital leukemia is a rare disease that can manifest soon after birth. Cutaneous involvement consists of red, brown or purple papules or nodules and purpura. We present a case of congenital myelomonblastic leukemia in a seven week old infant who had petechiae and subcutaneous nodules. Diagnosis was established by the presence of leukemic cells in bone marrow and involved skin along with cytochemical characterization of these cells.

Cutaneous Sarcoidosis.

We present a case of exclusive cutaneous sarcoidosis with no clinical or radiological evidence of disease anywhere else in the body.Exclusive cutaneous involvement is rare and is reported in about 4.5%patients of sarcoidosis.

Partial Androgen Insensitivity Syndrome.

Androgen insensitivity syndrome (AIS) present at several differentiation from genetic defects to end organ resistance thereby producing gender dilema dispelled by sex hormones signature.It is quite traumatic for the patients and family of the affected baby. Extreme sensitivity and awareness on the part of the caring doctor is necessary for early diagnosis of case of AIS &for successful outcome.

Metaplastic Carcinoma of Breast.

Metaplastic carcinoma of breast is a rare neoplasm. Although it is a tumor of ductal type, the predominent component may have an appearance other than the glandular pattern and usually runs an aggressive course.

Clinical Profile in H. Pylori Positive Patients in Jammu

The present prospective one year, study enrolled 265 symptomatic patients of acid peptic disease, out of which 92 patients were found H. pylori positive (by biopsy urease test and histopathological test) giving a prevalence of 34.71% . Among H. pylori positive patients, 64.13% were males and 35.86% were females. Age wise distribution showed maximum prevalence of H. pylori infection in the age group of 36-45 years and minimum in the age group of 66-75 years. Pain upper abdomen was the most frequent symptom in 49 (54.20%) patients followed by fullness after meals and retrosternal burning. Endoscopic and histopathological examination of H. pylori positive patients revealed chronic superficial gastritis in 87 (94.56%) patients followed by duodenitis in 11 (11.95%) and oesophagitis 8 (8.6%). All the positive patients were given anti-H. pylori treatment.

Gorlin's Syndrome-A case report.

Gorlin's syndrome is a rare disorder transmitted as an autosomal dominant trait. Most common phenotypic expression of this syndrome is a basal cell carcinoma (BCC). It is characterized by multiple skin lesions on head and neck region. We present a case of49 year old male who presented with basal cell carcinoma at multiple sites simultaneously.