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1.
Chinese Journal of Contemporary Pediatrics ; (12): 218-222, 2019.
Article Dans Chinois | WPRIM | ID: wpr-774097

Résumé

The pertussis surveillance system has been established since 2009 in Tianjin, and continuously improved over the past 10 years. This system determines the definition and classification of pertussis, establishes simple and feasible sampling methods and laboratory detection methods in clinical practice, standardizes the report management of pertussis cases and the treatment of epidemic situations. After the implementation of the surveillance system, the number of reported pertussis cases increased from 26 in 2009 to 802 in 2017, the number of diagnosed cases increased from 19 in 2009 to 662 in 2017, the reported incidence rate of pertussis increased from 0.16/100 000 in 2009 to 4.28/100 000 in 2017, and the number of medical institutions of reporting perutssis cases increased from 2 in 2009 to 53 in 2017. The specimen collection rate of the reported cases reached up to 93.66%. These results show that the sensitivity of pertussis surveillance has been improved and show that the data from the surveillance system may reflect more precisely the epidemical characteristics of perutssis in Tianjin.


Sujets)
Humains , Nourrisson , Incidence , Vaccin anticoquelucheux , Coqueluche
2.
China Journal of Chinese Materia Medica ; (24): 3745-3748, 2019.
Article Dans Chinois | WPRIM | ID: wpr-773657

Résumé

A new isobenzofuranone derivative was isolated from Chaenomeles sinensis by using various chromatographic techniques,including silica gel,Sephadex LH-20,MCI-gel resin and RP-HPLC. This compound was determined as 2,2-dimethyl-5-( 2-oxopropyl)-2 H-furo[3,4-h]chromen-7( 9 H)-one( 1) by NMR,MS,IR and UV spectra,and was also evaluated for its antibacterial activity. The results showed that it showed prominent antibacterial activity with MIC90 value of( 53. 7±4. 5) mg·L-1 for methicillin resistant Staphylococcus aureus( MRSA) strain. This value is close to that of levofloxacin [with MIC90 value( 50. 2± 4. 2) mg·L-1].


Sujets)
Antibactériens , Pharmacologie , Benzofuranes , Pharmacologie , Chromatographie en phase liquide à haute performance , Staphylococcus aureus résistant à la méticilline , Tests de sensibilité microbienne , Composés phytochimiques , Pharmacologie , Rosaceae , Chimie
3.
Biomedical and Environmental Sciences ; (12): 545-548, 2017.
Article Dans Anglais | WPRIM | ID: wpr-311379

Résumé

The epidemiologic characteristics of 631 infant pertussis cases < 12 months, which accounted for 57.42% of the total cases, were analyzed by descriptive epidemiology in Tianjin, between 2010 and 2015. The incidence of infants was 104.66/100,000, which was 118 times higher than in other age groups (P < 0.001). The primary type of pertussis simultaneously presented in households was adult-to-infant (70.51%). The parents were identified as the source of infection in 80.18% of cases for infants. The positive rate of placental antibody transfer was 31.06% and 3.13% for 3-month-old infants. Infants presented the highest age-specific pertussis incidence. The most important reason was parents were the important sources of infection, and secondly the lower level of antibodies in neonates and the rapid waning of maternal antibody titer.


Sujets)
Femelle , Humains , Nourrisson , Nouveau-né , Mâle , Chine , Épidémiologie , Vaccin anticoquelucheux , Allergie et immunologie , Facteurs de risque , Coqueluche , Épidémiologie
4.
China Journal of Orthopaedics and Traumatology ; (12): 340-342, 2010.
Article Dans Chinois | WPRIM | ID: wpr-297858

Résumé

<p><b>OBJECTIVE</b>To analyze the reasons and related factors of failures in the treatment of intertrochanteric fracture with dynamic hip screw (DHS) and to increase the therapeutic level of intertrochanteric fracture.</p><p><b>METHODS</b>All the 78 cases of intertrochanteric fractures were treated with dynamic hip screws from Dec. 1998 to Dec. 2007 included 42 males and 36 females with an average age of 62 years old ranging from 26 to 85 years. The disease course was from 1 to 49 hours (means 4 hours). According to Evans-Jensen classification of intertrochanteric fracture, 4 cases were type IA, 24 cases were type IB, 13 cases were type IIA, 22 cases were type IIB, 11 cases were type III, 4 cases were type IV. The fracture were fixed with dynamic hip screws following AO operative standard. To analyze the reasons and related factors of the 12 failed cases involving femur head and neck cut-off, tail pin exit, coxa vara, screw loosening, compress screw slip out of the tube, fracture displacement, respectively.</p><p><b>RESULTS</b>All the cases were followed up for 13 months to 7 years with an average of 36 months, 12 cases were failed including 4 cases of femur head and neck cut-off, 1 case of coax vara, 2 cases of compress screw slip out of the plate tube, 2 cases of screws loosening, 2 cases of tail pin displacement 1 case of great trochanter fracture displacement.</p><p><b>CONCLUSION</b>For intertrochanteric fracture, to interfix with dynamic hip screw is an effective method, the choice of indication, the type of fracture, the bone mineral density and the manipulative technique affect the results.</p>


Sujets)
Adulte , Sujet âgé , Sujet âgé de 80 ans ou plus , Femelle , Humains , Mâle , Adulte d'âge moyen , Vis orthopédiques , Analyse de regroupements , Études de suivi , Fractures de la hanche , Imagerie diagnostique , Chirurgie générale , Thérapeutique , Études rétrospectives , Tomodensitométrie , Résultat thérapeutique
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