Résumé
Human recombinant B type natriuretic peptide(hBNP) binds to receptor in the vasculature, kidney, and other organs to mimic the action of endogenous natriuretic peptides. Intravenous infusion of hBNP has been studied with acute decompensated heart failure. It causes potent, dose related vasodilation that is rapid in onset and sustained for the duration of drug infusion, reflected by decreases in systemic vascular resistance, systemic arterial pressure, pulmonary capillary wedge pressure, right atrial pressure, and mean pulmonary arterial pressure. Vasodilation occurs without a change in heart rate and is associated with increases in stroke volume and cardiac output. hBNP may promote diuresis because of a direct natriuretic action, increased cardiac output, and decreased aldosterone levels. For decompensated heart failure, hBNP improves symptoms and is well tolerated. The major adverse effect is dose related hypotension. As a new vasodilator, it should be valuable in treatment of patients hospitalized for decompensated heart failure.
Résumé
In order to reduce hospital acquired infection(HAI)caused by endoscopy examination,explore more effective administration,this article introduces a series of measures and effects about controlling the sources of infection,disinfecting the tool of anesthesia、endoscopy and its appendix、environment in our endoscopy center.
Résumé
This article introduces the centralized operation and integrated management of the Endoscopy Center of Nanjing General Hospital,expounding the idea of development,mode of management,working model and characteristic structure of the center.