Résumé
This study evaluated the abnormal lipid metabolism related to OCs usage among women with different ABO blood groups. It comprised 204 healthy women regularly using OCs for more than 1 year [56 group A, 52 group B, 24 group AB and 72 group O], as well as 82 healthy women not receiving any hormonal contraception or therapy [21 group A, 20 group B, 11 group AB and 30 group O]. The abnormal lipid changes related to OCs usage [elevated serum triglyceride, total cholesterol and LDL- chol] was found more among women with blood group A and B and no significant changes was found among women with blood group AB and only increase in serum triglycerides was found among women with blood group O. Although the altered lipid metabolism among women with blood group B, AB and O showed no relation to the estrogen content of pills, the lipid abnormalities among women with blood group A was related to the estrogen content of pills. It is advisable to estimate serum lipids for women with blood group A and B before using OCs and annually when using the pills. Women with blood group A should not receive the 50 mug estrogen containing pills. In absence of known contraindications, women with blood group AB and O could use any OCs preparation as a contraceptive method