The Potential use of Phenolic Compounds Recovered from Olive Mill Wastewater in Food Model Systems

In terms of economic growth, health benefits, and culture, the olive oil industry is a critical sector for many countries. However, olive mill wastewater (OMWW) is one of the most polluting by-products of the manufacture of virgin olive oil. Several studies have reported that OMWW is a valuable resource of usable compounds for recovery and valorization. Because of its high content of phenolic compounds, it may serve a significant function in food because of the phenolics' strong antioxidant value. The current paper provides a survey of OMWW's phenolic recovery methods, focusing on their application as active constituents in food products. In addition, this contribution provides an overview of key research describing the potentialities of OMWW phenolics in food model systems. The Scopus, Web of Science, and Science Direct databases were chosen as our paper references. Based on the available studies, traditional techniques like solvent extraction, membranes, and, more recently, innovative technologies that promise minimum impact on these phytochemicals’ compounds are used to recover phenolics from OMWW. Various food products, such as vegetable oils, bakery products, milk beverages, and meat products, can be fortified. All of these applications are based on phenolics' antibacterial and antioxidant properties to minimize food matrix alteration and contamination.

Les effets indesirables dus aux antibiotiques : etude retrospective sur trois ans au centre regional de pharmacovigilance de Sfax

Les effets indesirables aux antibiotiques constituent un reel probleme de sante publique. Dans ce travail; ont ete analyses la frequence; les types; les facteurs predisposant et la gravite des effets indesirables aux antibiotiques. Notre etude; de type retrospectif; porte sur les cas d'effets indesirables aux antibiotiques obtenus par notification spontanee au centre regional de pharmacovigilance de Sfax durant une periode de trois ans. Parmi 249 cas d'effets indesirables medicamenteux; 82 cas (32;93) ont ete lies aux antibiotiques. L'age variait de 5 a 86 ans. Il s'agissait de 55 femmes et de 27 hommes. Soixante dix effets indesirables lies aux antibiotiques (85.36) parmi 82 etaient de nature immunoallergique. Dans 60 cas (73.17); les patients avaient des antecedents medicaux: atopie; allergie medicamenteuse; maladies auto-immunes ou pathologies chroniques necessitant une polymedication. 54 patients (65.85) prenaient 3 medicaments ou plus. Les formes graves ont ete observees chez 12 patients parmi 82 (14.63). La polytherapie; les maladies chroniques et l'age avance sont des facteurs favorisant la survenue des effets indesirables aux antibiotiques. Nos resultats soulignent le risque augmente chez les sujets ayant un antecedent d'allergie a un antibiotique de developper une allergie a un autre antibiotique