Reaction Times in Schizophrenia / 신경정신의학

The reaction time(RT) has been known to reflect attention that controls the flow of information processing. Extensive research has demonstrated cognitive impairment in schizophrenia subjects using RT tasks. However, little work has been done examining the relative contribution of DT(decision time) and MT(motor time) to slowed RT in schizophrenics. Also, recent investigators have observed that schizophrenic patients exhibit larger intra-individual variability in RT than do normal comparison subjects. The purpose of this study, using multi-stimulus convergent RT task, was to explore the speed of RT, relative contribution of decision time(DT) and motor time(MT) to slowed RT, overall sequential profile in 25 repeated-time measurements in 10 schizophrenic out-patients and 10 normal control subjects. Overall reaction time and decision time were slower in schizophrenic subjects than in normal controls. The motor time was not shown to be significantly different between the two groups with 0.05 significance level, although there was some trend indicating schizophrenic subjects were slower consistently in repreated measurements over time. These results suggested that the slower reaction time in schizophrenic subjects was mostly determined by cognitive component, decision time rather than motor time. Sequential profile of repeated measurements showed greater intraindividual and interindividual variations in schizophrenics than in normal controls. These results indicate that high variabilities are not merely measurement errors but characteristic of schizophrenic psychopathology.

Depressive Symptoms in a Korean Rural Sample: Risk Factor and Factor Structure / 신경정신의학

OBJECTIVES: The rates, correlates, and factor structure of depressive symptoms in a Korean rural sample were examined using Korean version of the Center for Epidemiologic Studies Depression Scale(CES-D). METHODS: Door to door visiting survey was conducted by trained interviewers. A random cluster sample of 1,315 respondents, aged 30 and over completed the CES-D scale along with additional sociodemographic questionnaires. RESULTS: In this sample, mean CES-D score of male and female were 7.8 and 9.5, respectively, which were lower than those reported previously. Symptoms of depression were most common among the less educated, non-married and female according to ANCOVA. Age was not a significant risk factor for depressive symptoms. Different factor structures emerged from this sample as compared to other studies using this approach. Somatic symptoms and affective symptoms were combined as one factor and emotional hardship emerged as a separate factor. CONCLUSIONS: Symptom scores and risk factors were similar to the results reported in other countries but unique factor structures were found in this study. Further research is needed about the Korean depressive symptomatology and related areas.

An Analysis of 53 Cases of Chronic Subdural Hematoma

The authors collected 53 consecutive cases of chronic subdural hematoma which were diagnosed by carotid angiography and brain scanning. There were 39 males and 14 females. The mean age was 45.6 years old. 80% of all cases had a history of head injury and one of the clinical manifestations of increased intracranial pressure as well as contralateral hemiparesis. The most common site of hematoma was fronto-parietal region. 42 cases were treated with simple drainage and 11 cases with membranectomy. Post-op. course was excellent in all cases of simple drainage, but in 2 cases of membranectomy, recollection of hematoma developed after surgery.